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Mechanism of Antioxidant Activity of Selenium Nanoparticles Obtained by Green and Chemical Synthesis.
Int J Nanomedicine
March 2025
Heavy Ion Laboratory, University of Warsaw, Warsaw, Poland.
Background: Selenium nanoparticles (SeNPs) show high therapeutic potential. SeNPs obtained by green synthesis methods, using commonly available plants, are an attractive alternative to nanoparticles obtained by classical, chemical methods. The green synthesis process uses environmentally friendly reagents, which offer an eco-friendly advantage.
View Article and Find Full Text PDFComparing UV and Diesel Cutaneous Damage and Evaluating the Protective Role of a Topical Antioxidant Mixture Containing Vitamin C, E and Ferulic Acid.
Exp Dermatol
March 2025
Department of Animal Sciences, Plants for Human Health Institute, NC State University, Kannapolis, North Carolina, USA.
Cutaneous tissue is one of the main targets of outdoor stressors, and nowadays, the effect of pollution on skin conditions and premature skin ageing has been well correlated, although the exact effect that different pollutants have on the skin has not been well defined, especially when compared to other stressors. Among the air pollutants, UV radiation and particulate matter (PM) have been found among the most aggressive in terms of skin damage, inducing oxinflammatory responses, promoting degradation of extracellular matrix (ECM) components, and compromising the cutaneous defensive barrier. Topical application of technologies able to prevent oxidative damage is still one of the best approaches to protect our skin, and considering the well-known antioxidant network, application of an antioxidant mixture is more recommended than a single compound.
View Article and Find Full Text PDFAcute ivermectin toxicity on skin and brain tissue of adult albino rats: Evaluation of the role of Flumazenil and Vitamin C as new treatment modalities.
Food Chem Toxicol
March 2025
Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Cairo University, Kasr Alainy Street, Cairo 11562, Egypt. Electronic address:
Ivermectin, a natural antiviral drug, has been recommended for treating various diseases, including Coronavirus Disease 2019. This study aimed to evaluate the potential histopathological and biochemical changes in the skin and brain of adult albino rats treated with ivermectin, as well as the effectiveness of Vitamin C and flumazenil in their treatment. Thirty rats were divided into five treatment groups, each containing six rats.
View Article and Find Full Text PDFIntravenous Glutathione and Vitamin Supplementation Causing Stevens-Johnsons Syndrome: A Case Report.
J Burn Care Res
March 2025
Department of Surgery, MetroHealth Medical Center, Cleveland, Ohio, United States.
Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis are severe mucocutaneous reactions with high morbidity and mortality, most commonly triggered by prescribed medications. Here, we report a case of a 33-year-old female who developed Stevens-Johnson/Toxic Epidermal Necrolysis after receiving an IV vitamin infusion containing glutathione, vitamin C, and vitamin D. While not commonly associated with the development of Stevens-Johnson Syndrome glutathione has been previously reported to have been the inciting agent in Stevens-Johnson Syndrome cases.
View Article and Find Full Text PDFSmart application of silver nanoparticles in the treatment of chicken coccidiosis in combination with special supplement to alleviate its toxicity.
Vet Parasitol
March 2025
Department of Parasitology, Faculty of Veterinary Medicine, Cairo University, Giza 1221, Egypt.
This study investigated the efficacy of a locally formulated nano-silver particle (Ag-NPs) treatment for controlling Eimeria spp. in chickens. Various concentrations of Ag-NPs were evaluated for their ability to inhibit the sporulation of five Eimeria species oocysts in vitro, with LC and LC values determined.
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