Primary Objective: To establish empirical sub-types, based upon cognitive test results of individuals who had sustained traumatic brain injury.
Research Design: The study was retrospective, applying cluster analyses and associated statistical tests to an established database.
Methods And Procedures: Neuropsychological data from veterans with brain trauma were cluster analysed using the WAIS-R and Halstead-Reitan Battery (HRB). External validity of the cluster solutions was evaluated.
Experimental Interventions: The study was based upon use of an established database that contained cognitive test data and information regarding diagnosis and clinical history.
Main Outcomes And Results: The WAIS-R clusters described sub-groups with near normal function, preserved verbal but impaired problem-solving abilities or global impairment. The HRB clusters differed in level of performance with Near Normal, Moderately Impaired and Globally Impaired clusters. Cluster membership was associated with age and employment status, but not with neurological findings.
Conclusion: The outcome of traumatic brain injury is heterogeneous and mainly associated with demographic considerations.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3109/02699051003670882 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Design, modeling, and preliminary evaluation of a simple wrist-hand stretching orthosis for neurologically impaired patients.
Wearable Technol
December 2024
Department of Mechanical Engineering, Vanderbilt University, Nashville, TN, USA.
This work studies upper-limb impairment resulting from stroke or traumatic brain injury and presents a simple technological solution for a subset of patients: a soft, active stretching aid for at-home use. To better understand the issues associated with existing associated rehabilitation devices, customer discovery conversations were conducted with 153 people in the healthcare ecosystem (60 patients, 30 caregivers, and 63 medical providers). These patients fell into two populations: spastic (stiff, clenched hands) and flaccid (limp hands).
View Article and Find Full Text PDFCriticality is Associated with Future Psychotherapy Response in Patients with Post-Traumatic Stress Disorder-A Pilot Study.
Chronic Stress (Thousand Oaks)
January 2025
Brain Research and Innovation Centre, Ministry of Defence, Utrecht, the Netherlands.
Background: Trauma-focused psychotherapy is treatment of choice for post-traumatic stress disorder (PTSD). However, about half of patients do not respond. Recently, there is increased interest in brain criticality, which assesses the phase transition between order and disorder in brain activity.
View Article and Find Full Text PDFTargeted Therapeutics in Oncology and Neurology: Advances in Kinase Inhibition and Biomarkers for Brain Injury.
ACS Med Chem Lett
January 2025
Usona Institute, Fitchburg, Wisconsin 53711-5300, United States.
Innovations in pharmaceutical science drive new treatment approaches for cancer and brain injury. This Patent Highlight reviews findings from three patents focused on kinase inhibition in cancer therapy and using biomarkers to assess brain injury. By targeting key enzymes such as AKT1 and diacylglycerol kinase alpha (DGKα), these innovations offer new strategies for cancer treatment, particularly in cases of resistance to conventional therapies.
View Article and Find Full Text PDFProcedural pain management in neonates: A Narrative review.
Int J Crit Illn Inj Sci
December 2024
Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
Over the past three decades, awareness regarding pain management in neonates has risen significantly. It has been very well established that neonates can perceive, feel, and react to stimuli that cause pain and discomfort to them. Neonates admitted to neonatal intensive care units (NICUs) are repeatedly subjected to invasive treatments, most of which are painful.
View Article and Find Full Text PDFEmerging Implications of Serum Resolvin D2 as a Biochemical Marker for Severity Assessment and Prognosis Prediction Following Moderate-Severe Traumatic Brain Injury: A Prospective Cohort Study.
Neuropsychiatr Dis Treat
January 2025
Department of Neurosurgery, Changzhi People's Hospital, Changzhi, Shanxi Province, People's Republic of China.
Background: Resolvin D2 (RvD2), which exhibits anti-inflammatory properties, is neuroprotective. This study aimed to ascertain the potential of serum RvD2 level as a prognostic predictor of moderate-to-severe traumatic brain injury (msTBI).
Methods: In this prospective cohort study, serum RvD2 levels were measured in 136 patients with msTBI and 100 healthy controls.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!