Stereoselective synthesis of configurationally stable functionalized ethano-bridged Tröger bases.

Chem Commun (Camb)

Department of Organic Chemistry, Quai Ernest Ansermet 30, Ch-1211 Geneva 4, Switzerland.

Published: April 2010

New functionalized ethano-bridged Tröger bases are readily prepared using a simple alkylation/rearrangement sequence which affords configurationally stable derivatives as single stereoisomers (de > 96%).

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Source
http://dx.doi.org/10.1039/b925065dDOI Listing

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