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Prevalence and Determinants of Sensitisation to Neomycin in North-Eastern Italy, 1997-2021.
Contact Dermatitis
January 2025
Anna Belloni Fortina, University of Padua, Italy.
Background: Allergic contact dermatitis (ACD) induced by topical application of neomycin is frequently reported.
Objectives: This multi-center study investigated prevalence and determinants of neomycin sensitisations in 30 629 outpatients from North-eastern Italy during 1997-2021.
Patients And Methods: European baseline and extended Triveneto series were applied on the upper back of patients patch testing for suspected ACD and removed after 48 h.
Registries in allergy: Structure, target groups, and key findings of allergy-focused registries in Germany.
Allergol Select
December 2024
Division of Allergy and Immunology, Department of Dermatology, Venerology and Allergology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
In allergology, clinical registries fill knowledge gaps of epidemiology, mechanisms of allergic diseases, and real-world treatment outcomes. Considering the continuous rise of allergic diseases worldwide, registries become increasingly important for the optimization and harmonization of patient care. In the current review, we present four ongoing allergy-focused registries initiated in Germany.
View Article and Find Full Text PDFAnthropogenic Drivers of Small-Island Effects in Urban Remnant Woody Plants.
Plants (Basel)
December 2024
College of Landscape Architecture and Forestry, Qingdao Agricultural University, Qingdao 266109, China.
The positive relationship between species richness and area is a fundamental principle in ecology. However, this pattern deviates on small islands, where species richness either changes independently of area or increases at a slower rate-a phenomenon known as the Small-Island Effect (SIE). While the SIE has been well documented in natural ecosystem, its presence in highly fragmented and disturbed urban ecosystem remains unexplored, posing challenges for urban vegetation conservation.
View Article and Find Full Text PDFHypersensitivity to Lanolin: An Old-New Problem.
Life (Basel)
November 2024
Department of Allergology, Clinical Immunology and Internal Medicine, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Ul. Ujejskiego 75, 85-168 Bydgoszcz, Poland.
Lanolin is a fatty substance derived from sheep's fleece. The ancient Greeks used the moisturizing and skin-protective properties of this substance. The technique of industrial production of lanolin was developed in Germany in the 19th century.
View Article and Find Full Text PDFChemogenetic Inhibition of Prefrontal Cortex Ameliorates Autism-Like Social Deficits and Absence-Like Seizures in a Gene-Trap Haploinsufficiency Mouse Model.
Genes (Basel)
December 2024
Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD 57069, USA.
Background: (absent, small, or homeotic-like 1), a histone methyltransferase, has been identified as a high-risk gene for autism spectrum disorder (ASD). We previously showed that postnatal severe deficiency in the prefrontal cortex (PFC) of male and female mice caused seizures. However, the synaptic mechanisms underlying autism-like social deficits and seizures need to be elucidated.
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