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Left Ventrolateral Prefrontal Cortical Activity During Reward Expectancy and Mania Risk.
JAMA Psychiatry
January 2025
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
Importance: Mania/hypomania is the pathognomonic feature of bipolar disorder (BD). As BD is often misdiagnosed as major depressive disorder (MDD), replicable neural markers of mania/hypomania risk are needed for earlier BD diagnosis and pathophysiological treatment development.
Objective: To replicate the previously reported positive association between left ventrolateral prefrontal cortex (vlPFC) activity during reward expectancy (RE) and mania/hypomania risk, to explore the effect of MDD history on this association, and to compare RE-related left vlPFC activity in individuals with and at risk of BD.
Resistance training protects the hippocampus and precuneus against atrophy and benefits white matter integrity in older adults with mild cognitive impairment.
Geroscience
January 2025
Laboratory of Imaging and Biomarkers in Cognitive Disorders, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Mild cognitive impairment (MCI) refers to cognitive alterations with preservation of functionality. Individuals with this diagnosis have a higher risk of developing dementia. Non-pharmacological interventions, such as physical exercise, are beneficial for the cognition of this population.
View Article and Find Full Text PDFBilateral striatal necrosis in a case with ADAR1-related Aicardi Goutières Syndrome.
Neurol Sci
January 2025
Division of Pediatric Neurology, Ankara University Faculty of Medicine, Ankara, Turkey.
Brain modulatory effects of rehabilitation interventions in fibromyalgia: a systematic review of magnetic resonance imaging studies.
Neurol Sci
January 2025
International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan.
Objectives: Fibromyalgia imposes a considerable burden of disability worldwide, and its therapies include rehabilitation interventions. However, the overall brain modulatory effects of rehabilitation interventions and their effects on clinical improvements in patients with fibromyalgia remain unclear. This systematic review of magnetic resonance imaging studies synthesised evidence for the brain modulatory effects of rehabilitation in patients with fibromyalgia.
View Article and Find Full Text PDFIntra- and interobserver agreement in evaluation of image-defined risk factors on computed tomography in pediatric neuroblastoma.
Pediatr Radiol
January 2025
Izaak Walton Killam Health Centre, Halifax, Nova Scotia, B3K 6R8, Canada.
Background: Image-defined risk factors (IDRFs) were introduced to provide a consensus approach for pre-treatment risk stratification on computed tomography (CT) and magnetic resonance imaging (MRI) in patients with neuroblastoma.
Objective: To assess the intra- and inter-reader agreement of radiologists in identifying IDRFs on CT.
Materials And Methods: Approval for this retrospective study was granted by our institutional research ethics board with a waiver of consent.
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