Background: Common mental disorders, such as depression, anxiety disorder, and adjustment disorder, have emerged as a major public and occupational health problem in many countries. These disorders can have severe consequences such as absenteeism and work disability. Different interventions have been developed to improve the return-to-work of employees with common mental disorders, but still a large proportion of employees experiences health and work problems after their return-to-work. For this reason, the SHARP-at work intervention is developed to prevent a relapse of sickness absence among employees who have returned to work after a period of sickness absence because of common mental disorders. We aim to evaluate the effectiveness, cost-benefit and process of the intervention compared to care as usual.
Methods/design: The study is designed as a cluster-randomised controlled trial with randomisation at the level of the occupational physician. Employees who have returned to work after a period of sickness absence because of a common mental disorder are included in the study. Employees in the intervention group will receive the SHARP-at work intervention. The intervention focusses on active guidance of employees by occupational physicians during the first weeks of work after sickness absence. Employees in the control group will receive care as usual. Outcomes will be assessed at baseline and at 3, 6, and 12 months follow-up. The primary outcome is cumulative recurrent sickness absence days. Secondary outcome measures are mental health, work functioning, and coping. Adherence to the protocol, communication between stakeholders, and satisfaction with the treatment are the process measures assessed in both study groups. Cost-benefit is calculated from a societal perspective. Finally, prognostic factors for a relapse of sickness absence are investigated.
Discussion: This study goes beyond return-to-work by focussing on the prevention of recurrent sickness absence. The study incorporates not only outcomes on sickness absence and mental health but also on health-related work functioning. The results of this study can contribute to a further development of practice guidelines and the promotion of sustainable work participation.
Trial Registration: NTR1963.
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http://dx.doi.org/10.1186/1471-2458-10-132 | DOI Listing |
Epidemics
January 2025
Institute of Evolutionary Medicine, University of Zurich, Switzerland; Swiss School of Public Health SSPH+, Zurich, Switzerland; Crisis Competence Center, University of Zurich, Switzerland. Electronic address:
Background: Our study aims to enhance future pandemic preparedness by integrating lessons from historical pandemics, focusing on the multidimensional analysis of past outbreaks. It addresses the gap in existing modelling studies by combining various pandemic parameters in a comprehensive setting. Using Zurich as a case study, we seek a deeper understanding of pandemic dynamics to inform future scenarios.
View Article and Find Full Text PDFFront Antibiot
January 2024
Department of Biotechnology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan.
Multidrug-resistant organisms are bacteria that are no longer controlled or killed by specific drugs. One of two methods causes bacteria multidrug resistance (MDR); first, these bacteria may disguise multiple cell genes coding for drug resistance to a single treatment on resistance (R) plasmids. Second, increased expression of genes coding for multidrug efflux pumps, which extrude many drugs, can cause MDR.
View Article and Find Full Text PDFBMJ Open
December 2024
Department of Public Health, University of Helsinki, Helsinki, Finland.
Objectives: This study aimed to identify distinct trajectories of long-term sickness absence (LTSA, >10 consecutive working days) among young and early midlife Finnish employees who experienced pain at baseline. It also aimed to determine the pain characteristics and occupational and lifestyle factors associated with these LTSA patterns.
Design: Longitudinal occupational cohort study with register linkage.
Sangyo Eiseigaku Zasshi
January 2025
Division of Occupational and Environmental Health, Department of Social Medicine, Shiga University of Medical Science.
Objectives: Assessing the risk of employee health problems according to firm characteristics (e.g., industry) can be used by companies to identify groups of workers with health problems and develop health-related policies.
View Article and Find Full Text PDFJ Stroke Cerebrovasc Dis
January 2025
Department of Clincal Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.
Background: Stroke patients with large vessel occlusions risk long-term or permanent sickness absence. We aimed to analyze the proportions and days of sickness absence and disability pension in thrombectomy-treated patients.
Methods: A register-based nationwide longitudinal cohort study of stroke patients treated with mechanical thrombectomy in 2016-2021 in Sweden (identified through the Swedish Board of Health and Welfare procedural code for care interventions, KVÅ:AAL15).
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