Lipoproteins are a largely uncharacterized class of proteins in bacteria. In this study, metabolic labeling of bacteria with fatty acid chemical reporters allowed rapid profiling of lipid-modified proteins. We identified many candidate lipoproteins in Escherichia coli and detected a novel modification on YjgF. This chemical approach should facilitate future characterization of lipoproteins.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031127 | PMC |
| http://dx.doi.org/10.1021/ja101387b | DOI Listing |
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