The clinical efficacy of DynaMatrix extracellular membrane in augmenting keratinized tissue.

Int J Periodontics Restorative Dent

Division of Periodontology, Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts 02115, USA.

Published: April 2010

AI Article Synopsis

  • The study aimed to compare the effectiveness and practicality of using an extracellular matrix membrane (DynaMatrix) versus an autogenous gingival graft for increasing the width of attached keratinized tissue in patients with insufficient gingiva around mandibular teeth.
  • Both treatment methods resulted in a significant increase in keratinized gingiva, with DynaMatrix blending well into the surrounding tissue and showing better aesthetics compared to the grafts.
  • Histological analysis showed that both treatment sites had similar mature connective tissue and keratinized epithelium, suggesting DynaMatrix could be a viable option for gingival augmentation.

Article Abstract

This study was conducted to compare the efficacy and feasibility of an extracellular matrix membrane (DynaMatrix) with that of an autogenous gingival graft in increasing the width of attached keratinized tissue. Six patients with an inadequate amount of attached keratinized gingiva on the bilateral facial aspect of the mandibular posterior teeth were recruited for this study. The defect sites were randomly subjected to receive either test (DynaMatrix membrane) or control (autogenous gingival graft) treatment. Both test and control sites achieved a clinically significant increase in the amount of keratinized gingiva, and the DynaMatrix membrane-treated sites blended well with the surrounding tissue, with a better appearance when compared to the autogenous gingival grafted sites. The biopsy specimens of both test and control sites appeared to be similar histologically, with mature connective tissue covered by keratinized epithelium. The results of both clinical and histologic evaluations have suggested a potential application of an extracellular matrix membrane in achieving gingival augmentation.

Download full-text PDF

Source

Publication Analysis

Top Keywords

autogenous gingival
12
keratinized tissue
8
extracellular matrix
8
matrix membrane
8
gingival graft
8
attached keratinized
8
keratinized gingiva
8
test control
8
control sites
8
keratinized
5

Similar Publications

Beyond Bone Grafts: Exploring the Efficacy of Alternative Regenerative Therapies.

Cureus

November 2024

Department of Periodontology and Dental Implantology, Medical University of Varna, Varna, BGR.

Context A vast body of published literature examines and evaluates the properties of bone restorative materials in combination with other biomaterials or as stand-alone applications. If we exclude the studies investigating the effectiveness of regenerative therapy with enamel matrix derivative (EMD), in all other cases, bone regenerative materials are placed on a "pedestal." Therefore, the study we have initiated covers methods whose protocol does not use bone-repair materials.

View Article and Find Full Text PDF

Achieving the optimal emergence profile: the role of soft tissue grafting and pontic site development.

Br Dent J

December 2024

Specialty Registrar in Restorative Dentistry, Bristol Dental Hospital, Lower Maudlin Street, Bristol, BS1 2LY, UK.

Hard and soft tissue remodelling after tooth extraction may result in a concave profile at the subsequent edentulous ridge. This defect may result in a sub-optimal aesthetic transition zone between the soft tissue and the pontic, which may appear to sit on the ridge, rather than emanating from within the ridge, as would a natural tooth. To optimise aesthetics, pontic site augmentation (PSA) (increasing the volume at the pontic site) and pontic site development (PSD) (remodelling the tissue at the pontic site) may provide a solution.

View Article and Find Full Text PDF

Context and objective The main goal of periodontal therapy is to remove periodontopathogenic microorganisms and regenerate destructured periodontal tissues. Advances in biomaterials have improved the results of regenerative procedures. However, there is limited data available to determine the best material for vertical bone deformities treated with regenerative treatment.

View Article and Find Full Text PDF

Context The underlying principle of guided tissue regeneration (GTR) lies in the use of barrier membranes. Their role is key to this method, as they inhibit the rapid growth of epithelial and connective tissue cells, thus isolating the infrabony defects (IBDs) and ensuring the regeneration of slower-growing periodontal structures. The main disadvantages of resorbable membranes are related to their limited time of action and the need to use them in two layers, which increases the chance of a postoperative complication, i.

View Article and Find Full Text PDF

The goal of mucogingival surgery or periodontal plastic surgery is to preserve gingiva, remove aberrant frenum or muscle attachments, increase vestibular depth, and correct the denuded root surface. Recession coverage is indeed a challenging technique, whereas covering the exposed roots is not only important for aesthetic reasons but also for preventing further issues such as tooth sensitivity, root decay, and loss of supporting bone. A coronally advanced flap (CAF) is one of the most common procedures done for recession coverage because of the concept that the coronal advancement of a flap without tension to cover the exposed root surface or CAF with autogenous grafts results in bulk and improves the thickness of the gingival tissue, increasing the stability and aesthetics of the result.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!