Study Design: Retrospective study of 37 patients with traumatic central cord syndrome.
Objective: The purpose of this study is to review a series of patients with central cord syndrome and to introduce a classification system that is predictive of functional outcome.
Summary Of Background Data: Central cord syndrome is the most common incomplete spinal cord injury, yet a predictive classification system does not exist.
Methods: Thirty-seven patients with traumatic central cord syndrome had 1-year results of the motor portion of the Functional Independence Measurement (FIM) Score. Ten factors were analyzed for their predictive effect on the 1-year Motor FIM Score.
Results: There were 8 women and 29 men with a mean age of 55.1 years. The mean injury motor FIM was 21.9 and mean 1-year Motor FIM: 70.2 (P < 0.001). The following had a predictive effect on 1-year Motor FIM: Injury ASIA Motor Score (P < 0.013) and magnetic resonance imaging evidence of abnormal signal intensity (P < 0.007). Points were assigned to these factors, and patients were categorized as Central Cord Injury Scale (CCIS) 1, 2, or 3. CCIS 1: n = 6, mean 1-year Motor FIM = 40.8; CCIS 2: n = 19 and FIM = 72.4; and CCIS 3: n = 12 and FIM = 81.5. Each classification had an increasing percentage of patients who could walk without ever using a wheelchair and had independence in bladder and bowel function.
Conclusion: The CCIS is predictive of a patient's functional outcome at 1 year and has the potential to help patients and physicians establish realistic expectations for functional recovery based on ASIA Motor Score and magnetic resonance imaging findings.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/BRS.0b013e3181c15887 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Machine Learning and Experiments Revealed Key Genes Related to PANoptosis Linked to Drug Prediction and Immune Landscape in Spinal Cord Injury.
Mol Neurobiol
January 2025
Department of Orthopedics, The Fourth Medical Center, Chinese PLA General Hospital, Beijing, 100048, China.
Spinal cord injury (SCI) is a severe central nervous system injury without effective therapies. PANoptosis is involved in the development of many diseases, including brain and spinal cord injuries. However, the biological functions and molecular mechanisms of PANoptosis-related genes in spinal cord injury remain unclear.
View Article and Find Full Text PDFSimultaneous whole-brain and cervical spine imaging at 7 T using a neurovascular head and neck coil with 8-channel transceiver array and 56-channel receiver array.
Magn Reson Med
January 2025
Imaging Centre of Excellence, University of Glasgow, Glasgow, UK.
Purpose: To develop a 7T neurovascular head and neck (NVHN) coil with an extended longitudinal coverage of the brain and cervical spine, with eight transceiver (TxRx) channels and 56 receive (Rx) channels for dynamic parallel-transmit (pTx) applications.
Methods: A dual-row transceiver array with six elements in the upper row and two elements in the lower row was designed using combined electromagnetic and circuit optimization and constructed. A 56Rx array covering the brain and cervical spine was designed and combined with the transceiver array.
Acute hyperglycemia impedes spinal cord injury recovery via triggering excessive ferroptosis of endothelial cells.
Int J Biol Macromol
January 2025
The Institute of Life Sciences, Engineering Laboratory of Zhejiang Province for Pharmaceutical Development of Growth Factors, Wenzhou University, Wenzhou 325035, China; The Orthopaedic Center, The First People's Hospital of Wenling, Affiliated Wenling Hospital and School of Pharmaceutical Science, Wenzhou Medical University, Taizhou, Zhejiang 317500, China. Electronic address:
Spinal cord injury (SCI) is a serious central nervous system injury that often causes sensory and motor dysfunction in patients. Diabetes seriously destroys the blood spinal cord barrier (BSCB) and aggravates SCI. Ferroptosis is a new type of programmed cell death.
View Article and Find Full Text PDFEffects of spinal stimulation and short-burst treadmill training on gait biomechanics in children with cerebral palsy.
Gait Posture
January 2025
Department of Mechanical Engineering, University of Washington, Seattle, WA, USA; Center for Research and Education on Accessible Technology and Experiences, University of Washington, Seattle, WA, USA. Electronic address:
Background: Children with cerebral palsy (CP) have an injury to the central nervous system around the time of birth that affects the development of the brain and spinal cord. This injury leads to changes in gait neuromechanics, including muscle activity and joint kinematics. Transcutaneous spinal cord stimulation (tSCS) is a novel neuromodulation technique that may improve movement and coordination in children with CP when paired with targeted physical therapy.
View Article and Find Full Text PDFCanadian Association of Radiologists Central Nervous System Diagnostic Imaging Referral Guideline.
Can Assoc Radiol J
January 2025
North York General Hospital, Toronto, ON, Canada.
The Canadian Association of Radiologists (CAR) Central Nervous System Expert Panel is made up of physicians from the disciplines of radiology, emergency medicine, neurosurgery, and neurology, a patient advisor, and an epidemiologist/guideline methodologist. After developing a list of 24 clinical/diagnostic scenarios, a rapid scoping review was undertaken to identify systematically produced referral guidelines that provide recommendations for one or more of these clinical/diagnostic scenarios. Recommendations from 55 guidelines and contextualization criteria in the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) for guidelines framework were used to develop 51 recommendation statements across the 24 scenarios.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!