Severe metabolic acidosis secondary to coadministration of creatine and metformin, a case report.

Am J Emerg Med

Department of Emergency Medicine, Hazrat Rasool-e-Akram Hospital, Iran University of Medical Sciences and Health Services, Tehran, Iran.

Published: March 2010

It is known from studies in young athletes that creatine supplements have beneficial effects on muscular functional capacity, so it is being widely used as a performance-enhancing substance in both professional and amateur sports men and women. They are approved and considered relatively safe, but there have been a few case reports of renal dysfunction associated with their use. We present the case of a patient who developed acute renal failure and lactic acidosis while using creatine and metformin simultaneously.

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http://dx.doi.org/10.1016/j.ajem.2009.07.016DOI Listing

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