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Future of U.S. living donor liver transplant: Donor and recipient criteria, transplant indications, transplant oncology, liver paired exchange, and non-directed donor graft allocation.
Liver Transpl
January 2025
Division of Transplant Surgery, Department of Surgery, University of Washington, Seattle, Washington, USA.
Article Synopsis
- Living donor liver transplant (LDLT) has been growing in the U.S., providing a critical way to increase the number of available organs and reduce wait times for patients needing liver transplants.
- The transplant community is exploring ways to broaden eligibility for both donors and recipients, including using older donors and expanding criteria for candidates who might benefit from a transplant.
- There are promising opportunities for LDLT in transplant oncology, especially for patients with specific types of advanced cancer, while ongoing advancements in surgical techniques aim to enhance access to transplants for those with end-stage liver disease.
A New Framework for Co-Creating Telehealth for Cancer Care with the Patient Community.
Patient
September 2023
Global Colon Cancer Association, Washington, DC, USA.
The increased use of telehealth in cancer care during the coronavirus disease 2019 pandemic has added to our knowledge and experience of the modality with benefits in terms of efficacy, cost, and patient and healthcare professional experience reported. However, telehealth has also been found not to be universally available to all patients with cancer, nor to be appropriate for every healthcare interaction; additionally, not all patients prefer it. Now that coronavirus disease restrictions have essentially ended and an opportunity to re-assess telehealth provision in cancer care presents, we offer a framework that aims to ensure that the needs and preferences of the patient community are included in the development of telehealth provision.
View Article and Find Full Text PDFPersonalized diagnosis in suspected myocardial infarction.
Clin Res Cardiol
September 2023
Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Background: In suspected myocardial infarction (MI), guidelines recommend using high-sensitivity cardiac troponin (hs-cTn)-based approaches. These require fixed assay-specific thresholds and timepoints, without directly integrating clinical information. Using machine-learning techniques including hs-cTn and clinical routine variables, we aimed to build a digital tool to directly estimate the individual probability of MI, allowing for numerous hs-cTn assays.
View Article and Find Full Text PDFFinancial, policy, and ethical barriers to the expansion of living donor liver transplant: Meeting report from a living donor liver transplant consensus conference.
Clin Transplant
July 2023
Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Introduction: In October 2021, the American Society of Transplantation (AST) hosted a virtual consensus conference aimed at identifying and addressing barriers to the broader, safe expansion of living donor liver transplantation (LDLT) throughout the United States (US).
Methods: A multidisciplinary group of LDLT experts convened to address issues related to financial implications on the donor, transplant center crisis management, regulatory and oversight policies, and ethical considerations by assessing the relative significance of issues in preventing LDLT growth, with proposed strategies to overcome barriers.
Results: Living liver donors endure multiple obstacles including financial instability, loss of job security, and potential morbidity.
Dissociative Identity Disorder in a Non-Directed Kidney Donor.
J Acad Consult Liaison Psychiatry
October 2021
Professor of Psychiatry, Psychology, Epidemiology, Biostatistics, Nursing, and Clinical and Translational Science, Director, Clinical Epidemiology Program, Director, Quality of Life Research, Artificial Heart Program, Adult Cardiothoracic Transplantation, University of Pittsburgh School of Medicine and Medical Center, Pittsburgh, PA.
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