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Comparison of the efficacy of neoadjuvant chemotherapy and neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients: meta-analysis of randomized controlled trials.
Int J Surg
January 2025
Department of Gastrointestinal Surgery, Clinical Medical College and The First Affiliated Hospital of Chengdu Medical College, Chengdu 610500, Sichuan Province, China.
Background: Preoperative neoadjuvant chemoradiotherapy (nCRT) is considered to be the standard treatment strategy for locally advanced rectal cancer (LARC); however, the risk of adverse events and postoperative recurrence remains significant. This study aimed to evaluate the non-inferiority of neoadjuvant chemotherapy (nCT) compared with nCRT in patients with LARC and to assess the possibility of eliminating radiotherapy on the basis of guaranteed efficacy.
Materials And Methods: We searched the PubMed, Embase, and Cochrane Library databases to identify randomized controlled trials (RCTs) comparing the efficacy of nCRT and nCT for LARC.
High-resolution direct magnetic resonance imaging fistulography with hydrogen peroxide for diagnosing anorectal fistula: A preliminary retrospective study.
World J Radiol
January 2025
Department of Medical Imaging, Anqing Hospital Affiliated to Anhui Medical University, Anqing 246000, Anhui Province, China.
Background: Fistula-in-ano is an abnormal tunnel formation linking the anal canal with the perineum and perianal skin. Multiple imagining methods are available to evaluate it, among which magnetic resonance imaging (MRI) is the most advanced noninvasive preoperative method. However, it is limited in its visualization function.
View Article and Find Full Text PDFRectovaginal Fistula Repair Following Vaginoplasty in Transgender Females: A Systematic Review of Surgical Techniques.
Plast Surg (Oakv)
February 2025
Department Plastic and Reconstructive Surgery, MedStar Georgetown University Hospital, Washington, DC, USA.
Rectovaginal fistula (RVF) remains a complex complication following gender-affirming vaginoplasty. This review aims to evaluate RVF repair techniques and outcomes following vaginoplasty. A systematic review was performed per PRISMA guidelines.
View Article and Find Full Text PDFMicrobiota in patients with cefuroxime resistance and anal fistula revealed by 16S ribosomal DNA.
World J Gastrointest Surg
January 2025
Department of Anorectal Surgery, The Second Affiliated Hospital of Jiaxing University, Jiaxing 314000, Zhejiang Province, China.
Background: Anal fistula is increasingly prevalent due to modern lifestyle factors, and surgery remains the primary treatment. However, the rising incidence of antibiotic resistance, particularly to cefuroxime, complicates perioperative management. The role of gut microbiota in influencing this resistance is not well understood.
View Article and Find Full Text PDFGangrene Secondary to Perineal Invasion by Rectal Cancer: A Case Report and Literature Review.
Cureus
December 2024
Department of Surgical Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, CHN.
Colorectal cancer usually metastasizes through lymphatic, blood, and intraperitoneal implantation. However, rectal cancer combined with perineal invasion after treated with chemotherapy is very rare. The present case study is of a 53-year-old male patient with a history of rectal cancer who developed a recto-perineal fistula with redness, swelling, and pain in the scrotum after repeated chemotherapy.
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