We reviewed the epidemiologic features and trends for 771 cases of meningitis in Oman from January 2000 to December 2005. We found 69% were bacterial in origin and 13% were viral. Leading bacterial pathogens included Haemophilus influenzae (15%), Streptococcus pneumoniae (14%) and Nesseria meningitidis (12%). For 56% of patients with suspected pyogenic meningitis, no specific bacterial pathogen could be identified. Peak occurrence was in children under 2 years old. The incidence of H. influenzae type b decreased by almost 100% after implementation of the national immunization programme in 2001, while the incidence of cases caused by S. pneumoniae and N. meningitidis remained steady.
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Tissue Barriers
December 2024
Department of Biomedical Sciences, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia.
This review investigates the pathogenic processes through which crosses the blood-brain barrier (BBB) to cause meningitis, with a focus on the interaction with host receptors in the central nervous system (CNS). a primary cause of bacterial meningitis, utilizes unique receptor-mediated pathways to infiltrate the BBB. The bacterial interaction with the platelet-activating factor receptor (PAFR) and the polymeric immunoglobulin receptor (pIgR) is looked at in this study.
View Article and Find Full Text PDFChilds Nerv Syst
September 2024
Department of Neurosurgery, Sultan Qaboos University Hospital, Muscat, Oman.
Leptomeningeal cyst (LMC) is a known complication of pediatric head injury but has not been described following a craniotomy other than for craniosynostosis. We present the case of a 20-month-old boy who underwent craniotomy for a traumatic epidural hematoma. There was an inadvertent tear of the dura which was repaired with a pericranial patch and dural sealant.
View Article and Find Full Text PDFPediatr Infect Dis J
October 2024
Child Health Department, Sultan Qaboos University Hospital, Sultan Qaboos University, Oman Medical Specialty Board, Muscat, Oman.
Pediatr Infect Dis J
October 2024
Paediatric Department, Oman Medical Speciality Board.
Background: Group B Streptococcus (GBS) infection is the leading cause of neonatal morbidity and mortality worldwide. This study aims to investigate the incidence of invasive GBS disease among infants less than 90 days old in Oman and to describe their risk factors, clinical presentations and clinical outcomes.
Methods: We retrospectively collected the data of less than 90-day-old Omani infants with culture-positive GBS from sterile samples.
Gulf J Oncolog
January 2024
Department of Neurology & Neurosurgery - Montreal Neurological Institute, Faculty of Medicine, McGill University, QC, Canada, Montreal, Quebec, Canada.
Background: Stereotactic radiosurgery is a well-known and influential management option for meningioma. This article aims to highlight the most cited publications on this topic.
Methods: All Scopus articles published in English under Stereotactic radiosurgery and meningioma were sorted according to the number of citations.
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