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Prevalence of delirium in German nursing homes: protocol for a cross-sectional study.
BMJ Open
January 2025
German Centre for Neurodegenerative Diseases (DZNE), Witten, Nordrhein-Westfalen, Germany
Introduction: Delirium is a neuropathological syndrome that is associated with several negative outcomes. Nursing home residents are vulnerable to developing delirium. Valid prevalence data and associated factors are not yet available for Germany.
View Article and Find Full Text PDFThe Photoinduced Response of Antimony from Femtoseconds to Minutes.
Adv Mater
January 2025
Institute of Materials Physics, University of Münster, Wilhelm-Klemm-Str. 10, 48149, Münster, Germany.
As a phase change material (PCM), antimony exhibits a set of desirable properties that make it an interesting candidate for photonic memory applications. These include a large optical contrast between crystalline and amorphous solid states over a wide wavelength range. Switching between the states is possible on nanosecond timescales by applying short heating pulses.
View Article and Find Full Text PDFAdministration of Delphinidin to Improve Survival and Neurological Outcome in Mice After Cardiac Arrest and Resuscitation.
Antioxidants (Basel)
November 2024
Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Rostock University Medical Center, Schillingallee 35, 18057 Rostock, Germany.
Reactive oxygen species (ROS) play an important role in ischemia-reperfusion (I/R) after cardiac arrest and cardiopulmonary resuscitation (CA-CPR). Early administration of vitamin C at a high dose in experimental models resulted in less myocardial damage and had a positive effect on survival after resuscitation. Here, we postulated that the ROS scavenging activity of an anthocyanin (i.
View Article and Find Full Text PDFCDK5 interacts with MST2 and modulates the Hippo signalling pathway.
FEBS Open Bio
December 2024
Center for Drug Research, Ludwig-Maximilians-University Munich, Germany.
MST2 (STK3) is a major upstream kinase in the Hippo signalling pathway, an evolutionary conserved pathway in regulation of organ size, self-renewal and tissue homeostasis. Its downstream effectors are the transcriptional regulators YAP and TAZ. This pathway is regulated by a variety of factors, such as substrate stiffness or cell-cell contacts.
View Article and Find Full Text PDFMouse strain-specific habituation to oral metamizole administration.
Lab Anim
December 2024
Rudolf-Zenker-Institute of Experimental Surgery, University Medical Center, Germany.
When pain might occur during an animal experiment, sufficient analgesia is necessary. Metamizole is the third most used postoperative pain medication in animal research. The analgesic effect of metamizole is supposed to last 6-8 h in rodents.
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