AI Article Synopsis

  • The text discusses a case where a small intestinal biopsy from a patient with common variable immunodeficiency showed signs similar to graft-vs-host disease.
  • It includes details from immunohistochemical studies and follow-up information regarding the patient's condition.
  • The study highlights the rarity of such cases in literature, emphasizing the need for awareness of this condition in evaluating gastrointestinal biopsies.

Article Abstract

We report graft-vs-host disease-like histology in a small intestinal biopsy specimen that was obtained from a patient with common variable immunodeficiency and related T-cell defect. We include findings from immunohistochemical studies and follow-up information. Review of the literature yielded only a small number of histologically documented cases of this lesion without previous bone marrow transplantation. Awareness of this clinicopathologic entity is important in the interpretation of gastrointestinal biopsy specimens.

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