The authors report the case of a 66 year old man with a Boden stage I adenocarcinoma of the rete testis treated by orchiectomy and adjuvant chemotherapy. Lung metastases developed 46 months later and were responsible for death despite further chemotherapy. Adenocarcinoma of the rete testis is an exceptional tumour, as only 23 cases satisfying the criteria defined by Feek and Hunter have been reported in the literature. The prognosis is poor even in the apparently localized forms (5 year survival less than 25%) and local recurrences and lung and/or hepatic metastases are frequent. Radiotherapy and chemotherapy appear to have little value.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
A case of xanthogranulomatous epididymitis complicated by florid testicular cystic ectasia.
Urol Case Rep
January 2025
Department of Surgery, Mater Dei Hospital, Malta.
Xanthogranulomatous inflammation (XGI) is a rare, benign inflammatory condition of unclear pathogenesis, characterised by infiltration and subsequent destruction of normal tissue by lipid-laden macrophages together with lymphocytes and plasma cells. A 56-year-old gentleman was referred to the urology department of our hospital due to concerns that his right testicle felt firmer than his left over the preceding six months. He was investigated and subsequently underwent a right sided orchidectomy.
View Article and Find Full Text PDFAdenocarcinoma of the rete testis: clinicopathological study of 18 cases with emphasis on MET amplification and a review of the literature.
Histopathology
December 2024
State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Background: Knowledge regarding adenocarcinoma of the rete testis (ACRT) is extremely limited due to its scarcity.
Methods And Results: This study enrolled 18 patients with ACRT from multiple institutions. Clinicopathological and immunohistochemical features were investigated, together with a comprehensive review of 95 previously reported cases.
The ductal network in the human testis and epididymis: What belongs to which?
Clin Anat
November 2024
Klinik für Urologie, Universitätsklinikum Schleswig-Holstein, Lübeck, Germany.
Article Synopsis
- The testes and epididymis have a network of tubules responsible for sperm generation, maturation, nourishment, and transport, including the efferent ductules connecting the rete testis to the epididymis.
- There is a debate over whether the efferent ductules belong to the testicles or the epididymis, but clinical evidence supports their classification with the epididymis.
- Correctly identifying components of the epididymis is crucial for assessing testicular cancers, as infiltration by tumors can affect prognosis.
Mesonephric tubules expressing estrogen and androgen receptors remain in the rete ovarii of adult mice.
Cell Tissue Res
January 2025
Department of Anatomy, Tokyo Medical University, Shinjuku-Ku, Tokyo, Japan.
The rete ovarii and epoophoron in females are homologous structures of the rete testis and efferent/epididymal duct in males and are derived from the developing rete cells and mesonephric tubules, respectively. Sex steroid hormones play a critical role in reproductive function for both sexes, and we recently reported expression patterns of sex steroid receptors in developing male reproductive tracts. However, their expression patterns in females remain unclear.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!