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Evaluation of O-(2-[18F]-Fluoroethyl)-L-Tyrosine in the Diagnosis of Glioblastoma. | LitMetric
Objective : To assess the feasibility of synthesis of O-(2-[(18)F]-fluoroethyl)-l-tyrosine (FET), a new positron emission tomographic (PET) tracer described in several studies but not yet considered standard in management of glioma, in routine practice and to determine FET uptake in a homogeneous group of patients with suspected high-grade glioma.Design : Prospective nonrandomized trial.Patients : Twelve patients with suspicion of high-grade glioma.Results : The mean (SD) FET uptake ratio was 3.15 (0.72) for the 12 patients and 3.16 (0.75) for the 11 patients with glioblastoma.Conclusion : The initial results are promising and indicate that FET PET is a valuable and applicable tool for the imaging of high-grade glioma.
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