G-Pisa is an experiment investigating the possibility of operating a high-sensitivity laser gyroscope with area less than 1 m2 for improving the performances of the mirrors suspensions of the gravitational wave antenna Virgo. The experimental set-up consists of a He-Ne ring laser with a 4-mirror square cavity. The laser is pumped by an RF discharge where the RF oscillator includes the laser plasma to reach a better stability. The contrast of the Sagnac fringes is typically above 50% and a stable regime has been reached with the laser operating in either single mode or multimode. The effect of hydrogen contamination on the laser was also checked. A low-frequency sensitivity, below 1 Hz, in the range of 10(-8)(rad/s)/square root(Hz) has been measured.
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http://dx.doi.org/10.1109/TUFFC.2010.1456 | DOI Listing |
BMC Ophthalmol
January 2025
Department of Retina and Vitreous, Narayana Nethralaya, #121/C, 1st R Block, Chord Road, Rajaji Nagar, Bengaluru, Karnataka, 560010, India.
Background: Accurate localization of premacular hemorrhages (PMHs) is crucial as treatment strategies vary significantly based on whether the hemorrhage resides within the vitreous gel, subhyaloid space, or beneath the internal limiting membrane (ILM). This report outlines the clinical features, diagnostic findings, and treatment outcomes in a patient diagnosed with a PMH secondary to suspected Valsalva retinopathy.
Methods: This is a retrospective interventional case report.
Inflammation
January 2025
Department of Otorhinolaryngology, Dankook University College of Medicine, 201 Manghyang-Ro, Dongnam-Gu, Cheonan, 31116, Republic of Korea.
During nasal polyp (NP) development, activated T cells differentiate into T helper (Th) 1, Th2, and Th17 cells. Additionally, regulatory T cells (Tregs) that have an immune suppressive function are involved in the pathophysiology of chronic rhinosinusitis (CRS) with NP (CRSwNP). Tregs can act as effector cells that produce inflammatory cytokines, such as interleukin (IL)-17A.
View Article and Find Full Text PDFJ Hazard Mater
December 2024
State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China; International Joint Laboratory on Food Safety, Institute of Analytical Food Safety, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China. Electronic address:
Antibiotic resistance genes (ARGs) are markers of drug-resistant pathogens, monitoring them contributes to prevent resistance to drugs. The detection methods for ARGs including PCR and isothermal amplification are sensitive and selective. However, it may take several hours or cannot be used on spot.
View Article and Find Full Text PDFSci Rep
January 2025
Jilin Key Laboratory of Solid-State Laser Technology and Application, School of Science, Changchun, 130022, Jilin, China.
The response mechanism of a Four-Quadrant Photodetector (QPD) in an experimental setting was studied by irradiating a single QPD cell with a millisecond-pulsed laser. The response signal of the irradiated QPD cell varied with energy flux, pulse width, and applied bias, and comprised four main stages: an initial stage, decreasing barrier stage, holding stage, and recovery stage. Not only was the response signal of the irradiated cell affected by laser irradiation, but also the responses of the other three cells.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, No.1 East Jianshe Road, Erqi District, Zhengzhou, 450052, China.
Increasing evidence points toward an essential role for complement activation in the pathogenesis of diabetic kidney disease (DKD). However, the precise molecular mechanisms remain unclear, and the pathway predominantly contributing to complement activation in DKD is of particular interest. In this study, the glomerular proteome, especially the profiles of the complement proteins, was analyzed in kidney biopsies from 40 DKD patients and 10 normal controls using laser microdissection-assisted liquid chromatography-tandem mass spectrometry (LMD-LC-MS/MS).
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