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Evolving Immunotherapy Strategies in Gastrointestinal Neuroendocrine Neoplasms.
Curr Treat Options Oncol
January 2025
The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins and Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Treatment for neuroendocrine neoplasms (NENs) is tailored to the tumor's site of origin, grade, and differentiation. NENs are categorized into two main types: well-differentiated neuroendocrine tumors (NETs), which tend to grow more slowly and are less aggressive, and poorly differentiated neuroendocrine carcinomas (NECs), which are highly aggressive and harder to treat. Treatment options for NETs range from somatostatin analogues and mTOR inhibitors to peptide receptor radionuclide therapy (PRRT) with Lutetium-177 dotatate.
View Article and Find Full Text PDFProduct innovation of non-alcoholic barley-based teas and kombucha: Consumer preferences and emotional responses.
J Food Sci
January 2025
Department of Crop and Soil Science, Oregon State University, Corvallis, Oregon, USA.
This research explores consumer preferences and emotional reactions to beverages made from roasted barley and examines the possibility of launching a new product line featuring Streaker barley grown in the Pacific Northwest. Utilizing hedonic scales, just-about-right scales, and check-all-that-apply questions, a sensory evaluation was conducted. The study reveals two distinct consumer clusters, each exhibiting contrasting preferences and responses to novel beverages incorporating Streaker barley.
View Article and Find Full Text PDFAI for Corneal Imaging: How Will This Help Us Take Care of Our Patients?
Cornea
December 2024
Casey Eye Institute, Oregon Health & Science University, Portland, OR.
As artificial intelligence continues to evolve at a rapid pace, there is growing enthusiasm surrounding the potential for novel applications in corneal imaging. This article provides an overview of the potential for such applications, as well as the barriers we must overcome to realize it.
View Article and Find Full Text PDFBackground: Poverty is considered one of the social determinants of health (i.e., a range of social and environmental conditions that affect health and well-being) because of its association with significant health problems.
View Article and Find Full Text PDFModeling Heterogeneous Catalysis Using Quantum Computers: An Academic and Industry Perspective.
J Chem Inf Model
January 2025
Theoretical Chemistry, Vrije Universiteit, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands.
Heterogeneous catalysis plays a critical role in many industrial processes, including the production of fuels, chemicals, and pharmaceuticals, and research to improve current catalytic processes is important to make the chemical industry more sustainable. Despite its importance, the challenge of identifying optimal catalysts with the required activity and selectivity persists, demanding a detailed understanding of the complex interactions between catalysts and reactants at various length and time scales. Density functional theory (DFT) has been the workhorse in modeling heterogeneous catalysis for more than three decades.
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