Introduction: Renal oncocytomas are benign neoplasms derived from cells of the distal renal tubule, and comprise 5% to 7% of primary renal neoplasms. Oncocytomas are mostly asymptomatic, and the majority of tumors are discovered incidentally. In this case report, we present a case of a patient with a giant oncocytoma arising from her left kidney.
Case Presentation: We describe a 25-year-old Turkish woman who was admitted to our hospital with abdominal pain and a 3-year palpable abdominal mass, which was found present since her second pregnancy. Examination revealed a 15 x 20-cm mass in her abdominal cavity. Computed tomography revealed a mass with regular outlines, measuring 18 x 11 x 12 cm, associated with the left kidney, and causing marked hydroureteronephrosis. We excised the mass and performed a left nephrectomy on our patient. The immunohistopathology of the mass was consistent with renal oncocytoma. No local or distant metastasis was seen at 6 months postoperatively.
Conclusion: To the best of our knowledge, this is the second largest renal oncocytoma described in the English language literature. This is also the first reported giant oncocytoma that presented during pregnancy.
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| http://dx.doi.org/10.1186/1752-1947-4-52 | DOI Listing |
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Article Synopsis
- * They typically appear as well-defined, tan or mahogany masses with a central scar, and their histology features simple cell structures that indicate low malignancy risk.
- * A review of 17 studies showed that while there is potential for metastasis (to liver, bones, lungs), only 1.5% experienced disease progression, indicating that aggressive cancer behavior is not necessarily linked to oncocytomas.
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