[Factor V Leiden and C677T MTHFR thrombophilic mutations associated with hyperfibrinogenemia, persistent high CRP and leucocytosis in newborn baby with perinatal infection--a clinical case].

We present a clinical case of newborn baby with perinatal infection. Despite the solidity antibiotic therapy and good condition of the neonate, we observed hyperfibrinogenemia, persistent high CRP and leucocytosis. These inflammatory markers and the extravasation of blood during correction of anaemic syndrome draw attention to the role of other causal factors. DNA analysis for thrombophilic mutations identifies factor V Leiden and C677T MTHFR variant.