Background: Porous tantalum was recently introduced as a metallic implant material for total knee arthroplasty. Its porosity, low modulus of elasticity, and high frictional characteristics were expected to provide physiologic load transfer and relative preservation of bone stock. However, to our knowledge, the effect of a Trabecular Metal tibial component on bone mineral density has not been reported. The purpose of the present study was to compare the periprosthetic bone mineral density between patients managed with uncemented Trabecular Metal and cemented tibial components.
Methods: Twenty-eight knees receiving a Trabecular Metal tibial component and twenty-eight knees receiving a cemented cobalt-chromium tibial component had dual x-ray absorptiometry scans at two weeks preoperatively and at two weeks and six, twelve, eighteen, and twenty-four months postoperatively, to assess periprosthetic bone mineral density. All of the operations were performed by one surgeon through a medial parapatellar approach.
Results: None of the differences between the two groups in terms of preoperative bone mineral density in the femoral neck, wrist, lumbar spine, or knee were significant. In both groups, the bone mineral density in the tibia decreased postoperatively. However, the postoperative decrease in bone mineral density in the lateral aspect of the tibia was significantly less in knees with Trabecular Metal components than in knees with cemented tibial components at twenty-four months (mean and standard deviation, -6.7% +/- 22.9% compared with -36.8% +/- 24.2%; p = 0.002). At twenty-four months postoperatively, there was no significant difference between the two groups in terms of the Knee Society score, range of motion of the knee, or bone mineral density in the lumbar spine. No prosthetic migration or periprosthetic fracture was detected in either group.
Conclusions: The decrease in bone mineral density of the lateral tibial plateau was less in knees with a Trabecular Metal tibial component following total knee arthroplasty than in knees with a cemented tibial component. Additional research is needed to determine whether long-term clinical benefits are realized with the use of porous tantalum tibial components for total knee arthroplasty.
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http://dx.doi.org/10.2106/JBJS.H.01349 | DOI Listing |
Nutrients
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Department of Medicine, School of Clinical Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC 3168, Australia.
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December 2024
Division of Cardiology and Nephrology, Department of Internal Medicine, Asahikawa Medical University, 2-1-1-1 Midorigaoka-Higashi, Asahikawa 078-8510, Hokkaido, Japan.
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Molecules
December 2024
Department of Dental Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto 602-8566, Japan.
Mild hypophosphatasia (HPP) can be difficult to distinguish from other bone disorders in the absence of typical symptoms such as the premature loss of primary teeth. Therefore, this study aimed to analyze the crystallinity of hydroxyapatite (HAp) and the three-dimensional structure of collagen in HPP teeth at the molecular level and to search for new biomarkers of HPP. Raman spectroscopy was used to investigate the molecular structure, composition, and mechanical properties of primary teeth from healthy individuals and patients with HPP.
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Ward of Endocrinology, Metabolism and Internal Diseases Ward, University Clinical Hospital, 60-786 Poznan, Poland.
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December 2024
Department of Radiology, School of Medicine, Dokuz Eylül University, İzmir 35330, Türkiye.
Osteoporosis is a common disease of the skeletal system that increases the risk of fracture. The prevalence of osteoporosis has been increasing as the aging population increases, affecting more than 200 million people worldwide. This study aimed to shed light on the clinical impact of osteoporosis on women's health and quality of life by evaluating the prevalence and risk factors for this disease among postmenopausal women, using a 10-year dataset from a tertiary center.
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