At the China Institute of Atomic Energy, a central region model cyclotron has been constructed, which is dedicated for various experimental verifications to study beam properties. The design features of the ion source and injection line have already been described in other papers. We shall report here the results of the initial beam tests. A wire scanner is employed in the injection line to measure beam transverse sizes and these data can be used to fit the phase plane parameters after the ion source. Based on the beam tests results, the ion source built in 2003 has been improved recently. The improvement is mainly due to the repair of the multicusp field. From the ion source to the exit of the inflector, a transmission efficiency of 93% has been obtained for a continuous and low current input beam. It is also described here the experimental arrangement and the results.
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http://dx.doi.org/10.1063/1.3310277 | DOI Listing |
Biochem Soc Trans
January 2025
Departamento de Ciencias Médicas Básicas, Facultad de Ciencias de la Salud-sección Medicina, Universidad de La Laguna, Tenerife, ES-38071, Spain.
Large conductance voltage- and calcium-activated potassium channels (BK channels) are extensively found throughout the central nervous system and play a crucial role in various neuronal functions. These channels are activated by a combination of cell membrane depolarisation and an increase in intracellular calcium concentration, provided by calcium sources located close to BK. In 2001, Isaacson and Murphy first demonstrated the coupling of BK channels with N-methyl-D-aspartate receptors (NMDAR) in olfactory bulb neurons.
View Article and Find Full Text PDFRSC Adv
January 2025
Department of Food Technology, College of Agriculture Engineering Sciences, Salahaddin University-Erbil Erbil Kurdistan Region Iraq
Arsenic (As) contamination in groundwater has become a global concern, and it poses a serious threat to the health of millions of people. Groundwater with high As concentrations has been reported worldwide. It is widely recognized that the toxicity of As largely depends on its chemical forms, making As speciation a critical issue.
View Article and Find Full Text PDFPharm Nanotechnol
January 2025
Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, New York, United States of America.
Metallic nanostructures play a vital role in technological advancement, providing exceptional performance and improved adaptability in comparison to their bulk equivalents. Conventional synthesis techniques frequently depend on dangerous reducing agents to transform metal ions into Nanoparticles (NPs), which presents considerable environmental and health issues. In contrast, the approach of green synthesis, which emphasizes the use of non-toxic reagents, has garnered significant interest as a sustainable method for the fabrication of Metallic Nanoparticles (MNPs).
View Article and Find Full Text PDFMass Spectrom Rev
January 2025
School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.
Ionization and fragmentation are at the core of mass spectrometry. But they are not necessarily separated in space, as in-source fragmentation can also occur. Here, we survey the literature published since our 2005 review on the internal energy and fragmentation in electrospray ionization sources.
View Article and Find Full Text PDFEnviron Sci Technol
January 2025
Department of Environmental Science, Stockholm University, Stockholm 10691, Sweden.
The complex and dynamic nature of airborne fine particulate matter (PM) has hindered understanding of its chemical composition, sources, and toxic effects. In the first steps of a larger study, here, we aimed to elucidate relationships between source regions, ambient conditions, and the chemical composition in water extracts of PM samples ( = 85) collected over 16 months at an observatory in the Yellow Sea. In each extract, we quantified elements and major ions and profiled the complex mixtures of organic compounds by nontarget mass spectrometry.
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