Localized hepatosplenic sarcoidosis with an elevated serum CA-125 level.

ScientificWorldJournal

Department of Medicine, Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Published: February 2010

AI Article Synopsis

  • Sarcoidosis is a granulomatous disease mainly impacting the lungs and lymph nodes, with rare cases of it occurring without lung involvement.
  • There have been only five documented instances of sarcoidosis linked to elevated serum CA-125 levels in existing literature.
  • This report details a unique case of localized hepatosplenic sarcoidosis, confirmed through biopsy, which is the first of its kind to show elevated serum CA-125 levels.

Article Abstract

Sarcoidosis, a granulomatous disorder of unknown etiology, primarily affects the lungs and lymph nodes. Extrapulmonary disease without any pulmonary involvement is rare. Sarcoidosis with an elevated serum CA-125 level has only been reported five times in the literature. We describe a case of localized hepatosplenic sarcoidosis, confirmed by biopsy, with associated CA-125 elevation. In our review of the current literature, this is the first reported case of localized hepatosplenic sarcoidosis with associated serum CA-125 elevation.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763710PMC
http://dx.doi.org/10.1100/tsw.2010.36DOI Listing

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