Complete genome sequence of Bifidobacterium animalis subsp. lactis BB-12, a widely consumed probiotic strain.

J Bacteriol

Department of Physiology, Chr Hansen A/S, Hørsholm DK-2970, Denmark.

Published: May 2010

AI Article Synopsis

  • Bifidobacterium animalis subsp. lactis BB-12 is a widely used probiotic strain found in functional foods and supplements, proven effective in various clinical trials.
  • Its complete genome has been sequenced, revealing a single circular chromosome that contains nearly 1.94 million base pairs, 1,642 protein-coding genes, 4 rRNA operons, and 52 tRNA genes.
  • Understanding its genome will provide insights into the unique characteristics that contribute to its probiotic benefits.

Article Abstract

Bifidobacterium animalis subsp. lactis BB-12 is a commercially available probiotic strain used throughout the world in a variety of functional foods and dietary supplements. The benefits of BB-12 have been documented in a number of independent clinical trials. Determination of the complete genome sequence reveals a single circular chromosome of 1,942,198 bp with 1,642 predicted protein-encoding genes, 4 rRNA operons, and 52 tRNA genes. Knowledge of this sequence will lead to insight into the specific features which give this strain its probiotic properties.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863482PMC
http://dx.doi.org/10.1128/JB.00109-10DOI Listing

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