Hyperprolactinaemia in early psychosis-not only due to antipsychotics.

Prog Neuropsychopharmacol Biol Psychiatry

Psychiatric University Outpatient Department, Psychiatric University Clinics Basel, c/o University Hospital Basel, Petersgraben 4, CH-4031 Basel, Switzerland.

Published: October 2010

Hyperprolactinaemia is often found in patients with schizophrenia and usually considered a consequence of antipsychotics. Prolactin levels were measured in 43 At-Risk Mental State individuals (ARMS) and 26 patients with First Episode Psychosis (FEP). Hyperprolactinaemia was found in 25.6% of ARMS and 46.2% of FEP. Within 60 antipsychotic-naïve ARMS and FEP, hyperprolactinaemia was found in 26.7%. Hyperprolactinaemia may be pre-existing in a subgroup of patients with schizophrenia.

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http://dx.doi.org/10.1016/j.pnpbp.2010.02.019DOI Listing

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