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Primary extraskeletal osteosarcoma of rectal mesentery: a rare case and literature review.
World J Surg Oncol
January 2025
The Department of General Surgery, The Second Hospital of Jilin University, Changchun, 130041, China.
Background: Extraskeletal osteosarcoma (ESOS) is a rare kind of sarcoma with a low preoperative diagnosis and a poor prognosis. ESOS arising from abdominal mesentery is extremely rare. Increasing diagnostic methods and standardizing treatment protocols are crucial issues of ESOS.
View Article and Find Full Text PDFPrimary Visceral Ewing Sarcoma (Gastric and Bladder) with KIT Expression: A Report of Two Patients and a Differential Diagnostic Approach.
Int J Surg Pathol
January 2025
Pathology Department, University of Valencia, Valencia, Spain.
Extra-skeletal Ewing sarcoma is a rare tumor, most commonly occurring in the paravertebral region, extremities, retroperitoneum, and very rarely in visceral locations. We present two primary visceral Ewing sarcomas confirmed at the molecular level: one located in the stomach and the other in the bladder. Both tumors demonstrated strong and diffuse membranous CD99 expression, accompanied by variable KIT immunoreactivity.
View Article and Find Full Text PDFOrbital mesenchymal chondrosarcoma: a case report.
J Int Med Res
January 2025
Department of Orbital Disease and Ocular Plastic Surgery, The Second Hospital of Jilin University, No. 4026 Yatai Street, Changchun, Jilin Province, China.
Extraskeletal orbital mesenchymal chondrosarcoma is an extremely rare and highly aggressive tumor. We herein report a case involving a woman in her early 20s diagnosed with orbital mesenchymal chondrosarcoma. This case report aims to increase recognition and understanding of this condition.
View Article and Find Full Text PDFDiagnostic Challenge of Phenotypic Variability in COL2A1-Related Disorders: Four Novel Variants and Expanding the Clinical Spectrum.
J Clin Res Pediatr Endocrinol
January 2025
Department of Pediatric Endocrinology, Umraniye Training and Research Hospital, Istanbul, Türkiye.
Objective: Heterozygous COL2A1 gene mutations are associated with type 2 collagenopathies, characterized by a wide, diverse, and overlapping clinical spectrum in related diseases. Our goal is to describe the clinical, radiological, and molecular findings of patients with COL2A1-related dysplasia and investigate the phenotype-genotype correlation. We also aim to emphasize the challenge of categorizing COL2A1-related diseases with similar clinical and radiological phenotypes.
View Article and Find Full Text PDFPrimary breast osteosarcoma: A case report highlighting the importance of radiologic-pathologic correlation.
Radiol Case Rep
March 2025
Department of Radiology, Sanford USD Medical Center, Sioux Falls, SD, USA.
Osteosarcoma of primary breast origin is a rare form of malignancy. Imaging findings are nonspecific and often overlap with other differential considerations reinforcing the importance of radiologic-pathologic correlation for an accurate diagnosis. This case report details the clinical presentation, imaging findings, histopathological features, and therapeutic approach that transpired to diagnose and treat this rare malignancy.
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