Primary Objective: To compare the effects of written landmark, cardinal and left/right street directions on navigational success at the beginning of a walking route.
Research Design: Matched control group comparison design.
Methods And Procedures: This study compared navigational performance of 18 adults with acquired brain injury (ABI) to controls matched for gender, age and education. Participants followed written directions with landmark, cardinal or left/right directions at each of four locations. Dependent measures included accuracy, directness, stated confidence and preference.
Main Results: Participants with ABI demonstrated greater errors and hesitancy than controls when presented with cardinal and left/right directions. Both groups performed equally well with landmark directions. All participants stated preference for landmark directions. Participants with ABI were more likely to guess or become confused when following cardinal or left/right directions.
Conclusions: Landmarks served as a performance equalizer between groups for navigational performance at the start of a walking route. Implications for the design of navigational assistive tools and future research are discussed.
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http://dx.doi.org/10.3109/02699051003610425 | DOI Listing |
Nat Commun
February 2024
Division of Molecular Embryology, DKFZ-ZMBH Alliance, Deutsches Krebsforschungszentrum (DKFZ), 69120, Heidelberg, Germany.
Establishment of the left-right (LR, sinistral, dextral) body axis in many vertebrate embryos relies on cilia-driven leftward fluid flow within an LR organizer (LRO). A cardinal question is how leftward flow triggers symmetry breakage. The chemosensation model posits that ciliary flow enriches a signaling molecule on the left side of the LRO that promotes sinistral cell fate.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2023
Graduate Program in Integrative Neuroscience, University of Nevada, Reno, NV 89557.
The coordinate frames for color and motion are often defined by three dimensions (e.g., responses from the three types of human cone photoreceptors for color and the three dimensions of space for motion).
View Article and Find Full Text PDFCureus
June 2021
Neuro-Oncology, University of Mississippi Medical Center, Jackson, USA.
Gerstmann syndrome is a neurobehavioral syndrome characterized by four cardinal symptoms: acalculia, agraphia, finger-toe agnosia, and dysgraphia. The syndrome is caused primarily by lesions at the confluence of parietal, temporal, and occipital lobes, but also can involve the middle frontal lobe of the dominant hemisphere. Documented inciting lesions include stroke, tumor, hemorrhage, arteriovenous malformations, and seizures.
View Article and Find Full Text PDFJAMA Otolaryngol Head Neck Surg
June 2021
Department of Pediatrics, Washington University School of Medicine in St Louis, St Louis, Missouri.
Importance: Primary ciliary dyskinesia (PCD) is a rare, inherited condition involving motile cilia that line the upper and lower respiratory tracts, leading to chronic infections of the paranasal sinuses, middle ear, and bronchi that begin during infancy. Unfortunately, despite its early presentation, PCD is often recognized late.
Observations: People with PCD have diverse clinical manifestations, including chronic upper and lower respiratory tract disease, laterality defects, and subfertility.
J Anat
November 2020
Department of Anatomy, Tokyo Dental College, Tokyo, Japan.
Although left/right differences in a configuration of the pulmonary artery (PA) and its branches are well known, there is little information as to when and how such differences are established. Examination of serial sagittal sections of 25 embryos and fetuses at 6-7 weeks of gestation demonstrated that, at O'Rahilly stages 18-20, the right earliest first branch of PA originated in the anterior side of the upper lobar bronchus and overlay the upper bronchi, in contrast to the left branch which was located posteriorly and constricted medially by the upper posterior bronchus B1 + 2b. The right earliest branch was most likely to correspond to the future superior trunk, while the left branch might be a lingual artery.
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