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Dilemma in prevention of pertussis infection among infants under six months in China.
Expert Rev Vaccines
January 2025
Department of Expanded Program on Immunization, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.
Introduction: Pertussis poses a significant threat to infants under six months due to their immature immune systems, limited maternal antibody protection, and constraints in the vaccination schedule. Despite vaccination efforts, this group remains highly susceptible to severe complications. Addressing these challenges is crucial for improving the health outcomes of infants in China.
View Article and Find Full Text PDFHER2 regulates autophagy and promotes migration in gastric cancer cells through the cGAS-STING pathway.
Anticancer Drugs
January 2025
Department of General Surgery and Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center.
In gastric cancer, the relationship between human epidermal growth factor receptor 2 (HER2), the cyclic GMP-AMP synthase-stimulator of the interferon genes (cGAS-STING) pathway, and autophagy remains unclear. This study examines whether HER2 regulates autophagy in gastric cancer cells via the cGAS-STING signaling pathway, influencing key processes such as cell proliferation and migration. Understanding this relationship could uncover new molecular targets for diagnosis and treatment.
View Article and Find Full Text PDFTrends in Prostate Cancer Incidence and Mortality Rates.
JAMA Netw Open
January 2025
Department of Epidemiology and Biostatistics, University of California, San Francisco.
Importance: Incidence of distant stage prostate cancer is increasing in the United States. Research is needed to understand trends by social and geographic factors.
Objective: To examine trends in prostate cancer incidence and mortality rates in California by stage, age, race and ethnicity, and region.
Exploring Maternal Resilience among Predominantly Low-Income and Minoritized Women.
Matern Child Health J
January 2025
Department of Psychology, College of Arts and Sciences, Lehigh University, Bethlehem, USA.
Background: Research has increasingly explored maternal resilience or protective factors that enable women to achieve healthier maternal and child outcomes. However, it has not adequately examined maternal resilience using a culturally-relevant, socio-ecological lens or how it may be influenced by early-life stressors and resources. The current study contributes to the literature on maternal resilience by qualitatively exploring the salient multi-level stressors and resources experienced over the lifecourse by predominantly low-income and minoritized women.
View Article and Find Full Text PDFDoes Executive Functioning Moderate the Association Between Psychopathic Traits and Antisocial Behavior in Youth?
Res Child Adolesc Psychopathol
January 2025
Department of Psychiatry and Behavioral Health, Penn State College of Medicine, Hershey, PA, USA.
This study examined the interplay of psychopathic traits, executive functioning, and antisocial behavior among adjudicated youth, with a focus on the potential moderating role of executive function. The current study uses data from the Pathways to Desistance dataset was examined, utilizing the Psychopathy Checklist: Youth Version (PCL-YV) and the Stroop Color-Word Task to measure psychopathic traits and executive functioning, respectively. Violent and property offending frequencies were self-reported.
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