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Syringomyelia with Central Canal Enlargement Caused by Postoperative Inflammation after Surgery for Intradural Lumbar Disc Herniation.
NMC Case Rep J
December 2024
Department of Orthopedic Surgery, NHO Osaka Minami Medical Center, Kawachinagano, Osaka, Japan.
Intradural lumbar disc herniation (ILDH) is a very rare condition, with cerebrospinal fluid (CSF) leakage as a postoperative complication. The central canal of the conus medullaris was reported to communicate with the subarachnoid space through a caudal aperture; however, this aperture has never been observed in vivo. Herein, we report a case of L1/2 ILDH with postoperative spinal adhesive arachnoiditis and syringomyelia in which the communication considered to be a caudal aperture was detected.
View Article and Find Full Text PDFHigh-risk adverse events in two types of single inhaler triple-therapy: a pharmacovigilance study based on the FAERS database.
Front Pharmacol
January 2025
Respiratory Department, Xiyuan Hospital of Chinese Academy of Chinese Medical Sciences, Beijing, China.
Objective: Single inhaler triple therapy is widely used in Chronic Obstructive Pulmonary Disease (COPD) and asthma. This research aimed to analyze adverse events (AEs) associated with Budesonide/Glycopyrronium/Formoterol Fumarate (BUD/GLY/FOR) and Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI).
Methods: This is a cross-sectional study.
Exploring the utility of snRNA-seq in profiling human bladder tissue: A comprehensive comparison with scRNA-seq.
iScience
January 2025
Epigenetics & Molecular Carcinogenesis, M.D. Anderson Cancer Center, Houston, TX 77054, USA.
Single cell sequencing technologies have revolutionized our understanding of biology by mapping cell diversity and gene expression in healthy and diseased tissues. While single-cell RNA sequencing (scRNA-seq) has been widely used, interest in single-nucleus RNA sequencing (snRNA-seq) is growing due to its benefits, including the ability to analyze archival tissues and capture rare cell types that are challenging to dissociate. However, comparative studies across tissues have yielded mixed results, with some reporting enhanced cell type retention using snRNA-seq while others finding cell type identification to be challenging in snRNA-seq data.
View Article and Find Full Text PDF[Functional disorders of the lower urinary tract in diabetes mellitus].
Urologie
January 2025
Urologische Abteilung, Landesklinikum Korneuburg, Wiener Ring 3-5, 2100, Korneuburg, Österreich.
Type 2 diabetes mellitus is a well-known metabolic disease with increasing prevalence. Diabetic-related complications lead to different types of organ damage, some of which some of which are less well-known. In the lower urinary tract, a complex interplay of neuronal, myogenic, and urothelial dysfunction leads to functional disorders of the lower urinary tract, with disorders of bladder storage and bladder emptying being in the forefront.
View Article and Find Full Text PDFReport of a prostate abscess mistakenly diagnosed as benign prostatic hyperplasia.
J Surg Case Rep
January 2025
Department of Urology, The Second Hospital of Longyan, No. 8, Shuangyang West Road, Beicheng, Longyan, Fujian 364000, China.
Given the intricacy involved in diagnosing prostatic abscess and the associated risk of severe complications, we present a case involving a 72-year-old male patient initially suspected of urinary retention due to benign prostatic enlargement, only to reveal multiple prostatic abscesses during surgical intervention. The objective is to raise awareness among clinicians regarding the potential presence of latent prostatic abscess and to prevent the occurrence of serious complications. Timely implementation of aggressive antimicrobial therapy and surgical drainage has been shown to significantly enhance patient prognosis and mitigate the risk of serious complications.
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