AI Article Synopsis
- The study aimed to identify clinical characteristics that help differentiate which preterm infants can be treated with the INSURE method instead of needing mechanical ventilation (MV).
- Among 125 infants studied, 75 were treated with INSURE, achieving a 91% success rate, particularly in those with less severe respiratory distress syndrome (RDS) and lower rates of complications.
- Certain factors like low birth weight and specific blood gas measurements were linked to a higher risk of INSURE treatment failure.
Article Abstract
Objectives: Our aim was to identify the clinical characteristics which could distinguish infants who can be managed with INSURE (intubatio-surfactant-extubation) method for preventing mechanical ventilation (MV) and which could predict INSURE success or failure.
Methods: Inborn infants with gestational age <30 weeks were Infants were categorised into three groups: (1) infants who needed MV in the delivery room; (2) infants spontaneously breathing who were treated only with NCPAP; (3) infants who were treated with INSURE method.
Results: We studied 125 infants: 30 (24%) required MV, 75 (60%) received INSURE treatment, and 20 (16%) were treated with NCPAP. Sixty-eight (91%) infants were successfully treated with the INSURE method. Infants in the success group had less severe RDS and less occurrence of sepsis and pneumothorax, lower mortality, and shorter duration of stay in the NICU than infants in the failure group. A birth weight <750 g, pO(2)/FiO(2) <218, and a/ApO(2) <0.44 at the first blood gas analysis were independent risk factor for INSURE failure.
Conclusions: The INSURE method can be applied to the majority of extremely preterm infants and is followed by a high percentage of success.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3109/14767050903572174 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!