AI Article Synopsis

  • 1,2-Cyclic sulfamidates can be efficiently broken down in a specific way using aryllithium compounds.
  • This reaction allows for the creation of various N-substituted benzosultams.
  • The resulting compounds can be produced in diverse forms and are enantiopure, meaning they have a single chiral form.

Article Abstract

1,2-Cyclic sulfamidates undergo novel, efficient, and regiospecific intramolecular nucleophilic cleavage with aryllithiated species to provide an entry to poly-, diversely, and enantiopure N-substituted benzosultams.

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Source
http://dx.doi.org/10.1021/ol100288kDOI Listing

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