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ST-segment elevation is the hallmark of acute transmural myocardial ischemia caused by acute occlusion of a coronary artery. ST-segment elevation is the major criterion for the patients with chest pain to immediate reperfusion therapy. Despite its clinical importance, the mechanism of ST-elevation remains unclear. Two patients are reported with proximal left anterior descending coronary occlusion but without ST-segment elevation. The distinct ECG patterns were tall, with symmetrical T-waves and upsloping and digoxin-like ST-segment depression. Patients with these ECG patterns need immediate coronary intervention.
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http://dx.doi.org/10.1556/OH.2010.28807 | DOI Listing |
Ther Adv Cardiovasc Dis
March 2025
Healthy Heart Research Center, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Background: It is crucial to timely recognize individuals presenting high-risk characteristics indicative of acute myocardial infarction.
Objectives: Our study aimed to analyze the significance of evaluating ST-segment depression in patients with acute inferior myocardial infarction (MI). We assessed precordial ST-T changes as an indicator of ongoing ischemia, examined their correlation with the extent of coronary artery involvement, and potential association with both early and late cardiac outcomes.
Objective: This study aimed to assess the association between hemoglobin levels and in-hospital outcomes in patients with ST-segment elevation myocardial infarction (STEMI) at King Abdullah Medical City (KAMC).
Methods: This was a retrospective cohort study of 1,027 consecutive STEMI patients, from July 2022 to March 2023. The cohort was divided into two groups according to the presence of anemia on admission.
Front Cardiovasc Med
February 2025
Cardiology Department, The Second Affiliated Hospital of Shenyang Medical College, Shenyang, China.
Purpose: To evaluate the prognostic value of Low-density lipoprotein receptor-related protein 1 (LRP1) in patients with acute ST-segment elevation myocardial infarction (STEMI) following percutaneous coronary intervention (PCI).
Method: This prospective study included 96 STEMI patients who underwent PCI and 19 control subjects with normal coronary arteries. Coronary blood was taken from both groups, and LRP1 expression levels were quantified using real-time quantitative PCR (qPCR).
Cardiovasc Revasc Med
March 2025
Department of Cardiology, Leighton Hospital, Mid Cheshire Hospitals NHS Trust, Crewe, UK.
Background: The impact of timing of invasive coronary angiography (ICA) and management strategies on in-hospital outcomes among unselected all-comers with non-ST-segment elevation myocardial infarction (NSTEMI) presents an equipoise in clinical practice.
Methods: Patients with NSTEMI from the US NIS database during 2016 to 2021 were included in the analysis. In-hospital outcomes were examined according to the timing of ICA - early (<24 h), intermediate (24-72 h), and delayed (>72 h).
JACC Adv
March 2025
Cardiology and Angiology, Medical University of Innsbruck, University Clinic of Internal Medicine III, Innsbruck, Austria. Electronic address:
Background: Ischemia-reperfusion (I/R) injury patterns detected by cardiac magnetic resonance imaging after percutaneous coronary intervention (PCI) have important prognostic implications and trigger inflammatory processes that can further enhance myocardial tissue damage.
Objectives: The authors aimed to investigate the association of circulating inflammatory markers and I/R injury patterns in patients with ST-segment elevation myocardial infarction (STEMI).
Methods: This observational study included 456 STEMI patients.
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