Endocrine aspects of healthy brain aging.

Clin Geriatr Med

Department of Neurology and Psychiatry, Division of Geriatric Psychiatry, Saint Louis University, St Louis, MO 63104, USA.

Published: February 2010

AI Article Synopsis

  • The article discusses how hormones influence behavior and the connection between hormonal changes and mental health issues as people age.
  • It emphasizes the less obvious effects of hormonal changes on cognition, rather than just the clear psychiatric symptoms linked to endocrine disorders.
  • The focus is on dementia and mild cognitive impairment, which are significant concerns for older adults.

Article Abstract

There is a long history of hormones altering behavior and endocrinopathies playing a role in psychiatric disease. This article highlights the hormonal changes that occur with aging and the effects of these hormonal changes on the brain, concentrating not on the well-known psychiatric manifestations of endocrine diseases, but on the more subtle effects of hormones and metabolic alteration seen in many older persons. The article focuses predominately on the role of hormones in cognition, as dementia and mild cognitive impairment are major problems in the older individual.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cger.2009.12.004DOI Listing

Publication Analysis

Top Keywords

hormonal changes
8
endocrine aspects
4
aspects healthy
4
healthy brain
4
brain aging
4
aging long
4
long history
4
history hormones
4
hormones altering
4
altering behavior
4

Similar Publications

Background: Evidence indicates a wide range of andrological alterations in patients with the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) infection and Coronavirus Disease 2019 (COVID-19).

Aim: To provide an update on the andrological effects of SARS-CoV-2 infection and COVID-19.

Methods: PubMed/MEDLINE and Institutional websites were searched for randomized clinical trials, non-systematic reviews, systematic reviews, and meta-analyses.

View Article and Find Full Text PDF

Introduction: The presence of wounds in addition to the excision-induced wounds after severance from the stock plants is known to positively influence adventitious root formation of woody plant cuttings. Previous morphological studies highlighted laser wounding as a technique allowing to precisely control the decisive ablation depth. However, the biochemical processes involved in the response of rooting to the additional wounding remained unexplored.

View Article and Find Full Text PDF

Background: Senility influences fertility in women and companion animals, especially horses.

Aim: This study aimed to investigate the effect of aging in horses on the daily changes in the dominant follicle (DF) dynamics and hemodynamics, antimüllerian hormone (AMH), enzymes, antioxidants, and ovarian hormones during the estrous cycle.

Methods: Ovaries of old mares ( = 5, age >20 years) and young native mares ( = 6, age <10 years) were scanned during 6 different estrous cycles from March 2022 to August 2023 with Doppler ultrasound.

View Article and Find Full Text PDF

Transcriptome analysis reveals the genetic basis underlying the formation and seasonal changes of nuptial pads in Rana chensinensis.

BMC Genomics

December 2024

Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, 152 Luoyulu, Hongshan District, Wuhan, 430079, China.

Background: Nuptial pads, a typical sexually dimorphic trait in anurans, are located on the first digit of the male forelimb in Rana chensinensis and exhibit morphological changes synchronized with breeding cycles. However, the genetic mechanisms underlying its formation and seasonal changes remain poorly understood.

Results: To identify genes and biological processes associated with the development and seasonal variations of nuptial pads, we conducted a comprehensive transcriptome analysis on nuptial pads and hind toe skin across both sexes at different breeding periods in R.

View Article and Find Full Text PDF

Thyroid hormone receptor- and stage-dependent transcriptome changes affect the initial period of Xenopus tropicalis tail regeneration.

BMC Genomics

December 2024

Section On Molecular Morphogenesis, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA.

Background: Thyroid hormone (T3) has an inhibitory effect on tissue/organ regeneration. It is still elusive how T3 regulates this process. It is well established that the developmental effects of T3 are primarily mediated through transcriptional regulation by thyroid hormone receptors (TRs).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!