Recent work has demonstrated sub-diffraction limited focusing using time-reversal mirrors and sources in scattering media at microwave frequencies. We numerically investigate the possibility of observing analogous effects in the optical domain using small cylindrical scatterers of realistic dielectric materials combined with an enclosing optical phase conjugate mirror in two-dimensional geometries. Such focusing is possible but appears not to significantly exceed the focusing available from an equivalent homogenized material, and is highly sensitive to precise scatterer configuration.
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http://dx.doi.org/10.1364/OE.18.001487 | DOI Listing |
Adv Mater
January 2025
Third Institute of Physics - Biophysics, Georg August University, Friedrich-Hund Platz 1, 37077, Göttingen, Germany.
In the burgeoning field of super-resolution fluorescence microscopy, significant efforts are being dedicated to expanding its applications into the 3D domain. Various methodologies have been developed that enable isotropic resolution at the nanometer scale, facilitating the visualization of 3D subcellular structures with unprecedented clarity. Central to this progress is the need for reliable 3D structures that are biologically compatible for validating resolution capabilities.
View Article and Find Full Text PDFLiNbO domain structures have been widely applied in nonlinear beam shaping, quantum light generation, and nonvolatile ferroelectric memory. The recent developments in nanoscale domain engineering techniques make it possible to fabricate sub-diffracted nanodomains in LiNbO crystal for high-speed modulation and high-capacity storage. However, it still lacks a feasible and efficient way to characterize these nanoscale domains.
View Article and Find Full Text PDFNat Commun
December 2024
Max Planck Institute for the Science of Light, Erlangen, Germany.
Driven by human ingenuity and creativity, the discovery of super-resolution techniques, which circumvent the classical diffraction limit of light, represent a leap in optical microscopy. However, the vast space encompassing all possible experimental configurations suggests that some powerful concepts and techniques might have not been discovered yet, and might never be with a human-driven direct design approach. Thus, AI-based exploration techniques could provide enormous benefit, by exploring this space in a fast, unbiased way.
View Article and Find Full Text PDFExpansion microscopy (ExM) enables sub-diffraction imaging by physically expanding labeled tissue samples. This increases the tissue volume relative to the instrument point spread function (PSF), thereby improving the effective resolution by reported factors of 4 - 20X [1, 2]. However, this volume increase dilutes the fluorescence signal, reducing both signal-to noise ratio (SNR) and acquisition speed.
View Article and Find Full Text PDFNanophotonics
July 2024
Department of Materials Science and Engineering , Texas A&M University, College Station, TX 77843, USA.
The emerging field of photonic topological insulators offers promising platforms for high-performance optical communication, computing, and sensing. However, conventional photonic topological insulator designs typically operate within the diffraction limit due to their dielectric nature. This limitation imposes constraints on device miniaturization, reduces light-matter interaction, and decreases overall device sensitivity.
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