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Correction: Are socio-economic inequalities related to cardiovascular disease risk? A systematic review and meta-analysis of prospective studies.
BMC Cardiovasc Disord
January 2025
Africa Unit for Transdisciplinary Health Research (AUTHeR), North-West University, Potchefstroom, South Africa.
The opportunities in implementing assistive technology in oral health care for individuals with sensory impairments: a systematic review.
Eur Arch Paediatr Dent
January 2025
Department of Restorative Dentistry, College of Dentistry, Jouf University, Sakaka, Saudi Arabia.
Purpose: People with sensory impairments (SI) face unique challenges in out-of-home care, especially in oral health (OH) care, compared to the general population. Various assistive technologies (ATs) and media are used to influence OH behaviors and outcomes for individuals with SI. This systematic review (SR) aimed to identify the types of ATs and assess their effectiveness for individuals with SI.
View Article and Find Full Text PDFAlleviation of liver fibrosis by inhibiting a non-canonical ATF4-regulated enhancer program in hepatic stellate cells.
Nat Commun
January 2025
Zhejiang Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang Key Laboratory of Frontier Medical Research on Cancer Metabolism, Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, China.
Liver fibrosis is a critical liver disease that can progress to more severe manifestations, such as cirrhosis, yet no effective targeted therapies are available. Here, we identify that ATF4, a master transcription factor in ER stress response, promotes liver fibrosis by facilitating a stress response-independent epigenetic program in hepatic stellate cells (HSCs). Unlike its canonical role in regulating UPR genes during ER stress, ATF4 activates epithelial-mesenchymal transition (EMT) gene transcription under fibrogenic conditions.
View Article and Find Full Text PDFDiet-wide analyses for risk of colorectal cancer: prospective study of 12,251 incident cases among 542,778 women in the UK.
Nat Commun
January 2025
Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Uncertainty remains regarding the role of diet in colorectal cancer development. We examined associations of 97 dietary factors with colorectal cancer risk in 542,778 Million Women Study participants (12,251 incident cases over 16.6 years), and conducted a targeted genetic analysis in the ColoRectal Transdisciplinary Study, Colon Cancer Family Registry, and Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO).
View Article and Find Full Text PDFMeeting of Knowledges: Critical Interculturality and Collective Health.
Cien Saude Colet
December 2024
Universidade Federal do Sul da Bahia. Itabuna BA Brasil.
The National Policy for the Care of Indigenous Peoples (NPCIP) faces an enormous challenge in operationalization regarding the training and qualification of health professionals to work in an intercultural context. In this article, we open a dialogue with the proposal of a Meeting of Knowledges (MK) as a teaching and learning strategy capable of promoting a critical intercultural education. We seek to reflect on the possible impact of MK in the health field for transforming the university environment, as well as healthcare for Indigenous communities, towards an entrenched, democratic, pluriepistemic, and transdisciplinary perspective.
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