The design, synthesis and evaluation of methyl 1,2,8,8a-tetrahydrocyclopropa[c]oxazolo[2,3-e]indol-4-one-6-carboxylate (COI) derivatives are detailed representing analogs of duocarmycin SA containing an oxazole replacement for the fused pyrrole found in the alkylation subunit.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965170 | PMC |
| http://dx.doi.org/10.1016/j.bmcl.2010.01.145 | DOI Listing |
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