Objectives: The effects of interactions between cross-linking proanthocyanidins (PA) in polar solvents and type-I collagen of demineralized dentin were investigated.
Methods: Three PA-rich extracts, two from grape seed (GSEP and GSES) and one from cocoa (COE), were dissolved (water, ethanol:water and acetone:water) and analyzed for their ability to increase the modulus of elasticity of demineralized dentin. Sound dentin beams (0.5mmx1.7mmx7mm) were fully demineralized and divided into 12 groups according to the type of cross-linking agent and solvents used. Specimens were immersed in the respective solutions and tested at baseline, 10, 30, 60, 120 and 240min.
Results: The elastic modulus (EM) of dentin was significantly increased by the PA treatment regardless of time (p<0.05 for all times). The extracts showed different solubility in different solvents. GSEP showed the highest increase in EM when diluted in distilled water and acetone at all exposure times. Both GSEs showed superior results when diluted in distilled water and after 4h of treatment, while COE produced strongest enhancement when dissolved in ethanol:water.
Conclusions: The results indicates that herbal extraction process and other pharmacognostic parameters have an important influence on extract solubility as well as constitution and, consequently, on the PA-dentin matrix interaction.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882861 | PMC |
| http://dx.doi.org/10.1016/j.jdent.2010.02.002 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Osteoclastogenesis markers in craniofacial bone defects after demineralized dentin material membrane implantation as guided bone regeneration.
J Appl Oral Sci
January 2025
Universitas Airlangga, Faculty of Dental Medicine, Department of Oral Biology, Surabaya, East Java, Indonesia.
Unlabelled: Guided bone regeneration (GBR) is an alternative treatment for craniofacial bone defects reconstruction through membrane barrier adaptation, such as demineralized dentin material membrane (DDMM). DDMM is used as a substitute for GBR material, which aligns with Green Economy principles, it has a good biological osteoinductive and osteoconductive effects, and its structure resembles bones. The balance of bone remodeling when experiencing craniofacial defects will be altered and allow changes to resorption activity, so the mechanisms of osteoclastogenesis and bone resorption are vital.
View Article and Find Full Text PDFIs ADDM graft practical? A comparative study to evaluate ADDM graft in third molar surgery.
Oral Maxillofac Surg
January 2025
Teerthanker Mahaveer University, Morādābād, India.
Background: It has been outlined that LTM (Lower third molar) extracted from patients in which grinding, cleaning, sterilization & demineralization prove to be highly effective as graft material for filling the alveolar socket of the very same patient. These investigations aim to assess the efficiency of ADDM (Autogenous Demineralized Dentin Matrix) graft in third molar extraction sockets.
Purpose: To check the effectiveness of ADDM as graft material in extraction socket by evaluating pain, swelling, trismus, PD (Probing Depth) and bone density.
High-intensity focused ultrasound: an innovative approach for micro-manipulation of demineralized dentine.
J Transl Med
January 2025
Dental School, The University of Western Australia, 17 Monash Avenue, Nedlands, WA, 6009, Australia.
Background: Treatment of deep carious lesions poses significant challenges in dentistry, as complete lesion removal risks compromising pulp vitality, while selective removal often reduces the longevity of restorations. Herein, we propose a minimally invasive approach using High-Intensity Focused Ultrasound (HIFU) for microscale removal of carious dentine. Concurrently, HIFU's antimicrobial effects against associated cariogenic biofilms and the corresponding thermal and biological impacts on surrounding tissues were investigated.
View Article and Find Full Text PDFAlveolar ridge preservation with autogenous tooth graft: A histomorphometric analysis of 36 consecutive procedures.
Ann Anat
January 2025
Department of Dental Clinical Specialties, Faculty of Dentistry, Complutense University of Madrid, Spain; Surgical and Implant Therapies in the Oral Cavity Research Group; University Complutense, Madrid, Spain.
Background: The aim of this study was to analyze the histomorphometric findings of autogenous tooth grafting (ATG) for alveolar ridge preservation (ARP), using graft material from extracted teeth. Variations by sex, age and location of extracted teeth, as well as any associated complications, were also assessed.
Materials And Methods: This prospective, single-cohort study was conducted using ATG placed in extraction sockets.
Shear bond strength evaluation of bioactive restorative materials on pretreated carious dentin-influence on silver diamine fluoride, potassium iodide, and glutathione.
J Conserv Dent Endod
November 2024
Department of Conservative Dentistry and Endodontics, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India.
Background: Silver diamine fluoride (SDF) has gained popularity for its caries-arresting properties, yet its tendency to cause esthetic concerns due to black-staining limits its widespread acceptance.
Aim: The aim of the study was to evaluate and compare the shear bond strength of Activa BioActive and Giomer restorative material with different protocols of SDF pretreatment on carious dentin.
Materials And Methods: Ninety-two extracted teeth were decoronated at the cementoenamel junction, sectioned 1 mm into dentin, mounted in acrylic resin and randomly divided into four ( = 8) control and six ( = 10) experimental groups.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!