Introduction: The objective of this study is to analyze data related to hospitalization, comorbidities, fatality rate, average stays, and costs associated with hospitalized cases of acute hepatitis B in Spain, during 2001-2006.
Methods: A retrospective study to analyze the characteristics of acute hepatitis B patients admitted to Spanish hospitals was performed using the minimum basic data set. Costs were calculated using the diagnosis-related groups for the disease.
Results: The total number of hospitalized patients diagnosed with acute hepatitis B was 2160, of which 73.8% were diagnosed in men. The highest rate corresponds to the group aged 20-39 years (2.33/100 000 inhabitants). Ninety deaths (4.2%) were reported out of the total hospitalized patients. The average hospital stay was 10 days. The trends in the rate of hospitalized acute hepatitis B cases were not statistically significant. There were no differences found in the average length of stay or in the cost during the study period. The estimated total cost was 7 451 098 euros.
Conclusion: The rate of hospitalized acute hepatitis B patients in Spain did not change during the 2001-2006 period. Having an adequate surveillance system and continuing with the universal immunization and risk group programs, and health education, remain a high priority.
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http://dx.doi.org/10.1097/MEG.0b013e32833783b4 | DOI Listing |
Rev Med Chil
June 2024
Departamento de Gastroenterología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Liver transplantation (LT) is a cost-effective therapy for advanced liver disease. Although LT significantly improves long-term survival, it requires strict control of immunosuppressants and their potential complications. Several available immunosuppressive drugs include glucocorticoids, calcineurin inhibitors, mycophenolate, mTOR inhibitors, and anti-CD25 antibodies.
View Article and Find Full Text PDFFront Epidemiol
December 2024
College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia.
Background: Hepatitis B virus (HBV) infection poses a significant global health challenge, leading to approximately 1.1 million deaths annually. Informal caregivers of HBV patients face an increased risk of exposure, yet there is limited research on their awareness and infection prevention practices.
View Article and Find Full Text PDFCureus
December 2024
General Medicine, All India Institute of Medical Sciences, Nagpur, Nagpur, IND.
Autoimmune hepatitis (AIH) is a distinct clinical entity with variable presentations and diverse clinical outcomes, characterized by autoimmune-mediated injury to the liver. The detection of autoantibodies and histological features consistent with autoimmune injury is crucial for diagnosing AIH. Early identification and treatment are essential to prevent progression to cirrhosis.
View Article and Find Full Text PDFIran J Public Health
December 2024
Department of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Background: Phlebotomy has been used as a non-pharmacological treatment for different types of diseases, regarding the philosophy of humors in traditional medicines, such as Persian Medicine. However, according to the narrow-approved indications for phlebotomy in Western Medicine, we aimed to systematically summarize high-level of evidence on safety and efficacy of phlebotomy in treatment of human diseases.
Methods: In this umbrella review, to identify meta-analysis studies of clinical trials on phlebotomy, four electronic databases, including PubMed, web of science, Scopus, and Cochran library were searched until Jun 18, 2022 with relevant keywords for 'phlebotomy' and 'meta-analysis' according to PRISMA guidelines and PICO questions.
Zhejiang Da Xue Xue Bao Yi Xue Ban
December 2024
College of Public Health, Hengyang Medical School, University of South China, Hengyang 421001, Hunan Province, China.
As the central organ of metabolism, the liver plays a pivotal role in the regulation of the synthesis and metabolism of various nutrients within the body. Ferroptosis, as a newly discovered type of programmed cell death caused by the accumulation of iron-dependent lipid peroxides, is involved in the physiological and pathological processes of a variety of acute and chronic liver diseases. Ferroptosis can accelerate the pathogenetic process of acute liver injury, metabolic associated fatty liver disease, alcoholic liver disease, viral hepatitis, and autoimmune hepatitis; while it can slower disease progression in advanced liver fibrosis and hepatocellular carcinoma.
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