AI Article Synopsis
- Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for depression, particularly in patients with vascular depression.
- A study found that increased theta brain wave activity in the anterior cingulate cortex (ACC) may predict how well patients respond to rTMS treatment.
- The research involved 65 participants and utilized the Hamilton Depression Rating Scale to assess outcomes, showing promising results for those with vascular depression and a correlation between low-theta power in the ACC and treatment response.
Article Abstract
Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for depression. Increased metabolism in the anterior cingulate cortex (ACC) is a known predictor for antidepressant response. The authors assessed whether increased theta power within the ACC predicts rTMS response in participants with vascular depression. Sixty-five participants were randomized to active or sham rTMS. Outcome was assessed using the Hamilton Depression Rating Scale. Electroencephalography was obtained, and comparisons were made among each group with a normative database using low-resolution electromagnetic tomography. Results suggest that vascular depression participants respond well to rTMS and that increased low-theta power in the subgenual ACC predicts response to rTMS.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688059 | PMC |
| http://dx.doi.org/10.1176/jnp.2010.22.1.75 | DOI Listing |
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