Postoperative esophageal leak is still a very serious and complex problem, which is associated with poor results, because of considerable morbidity and mortality rate. We described the case of successful treatment of suture line leak of 53 year old patient after resection of a big size epiphrenic diverticulum. Traditional right-sided transthoracic approach in 7th intercostal space with dissection, exposure and resection of diverticulum by stapler with 40F bougie within the esophagus was performed with reinforcement of suture line. On 6th postoperative day the control water-soluble contrast X-ray examination was done and pleural effusion and suture line disruption was found. Immediately under X-ray control the large diameter chest tube (Ch24) was inserted and periesophageal mediastinum as well as pleural cavity was drained and active aspiration with simultaneously irrigation/lavage procedures was started. Parallel fasting, systemic antibiotic therapy was started and feeding balloon catheter gastrostomy by Stamm was created. The healing process of the leak was controlled every week by water-soluble contrast swallow and the chest drain tubes were twice changed (Ch20 and Ch14) during the treatment. The complete healing and closure of the leak was achieved after 2,5 month of starting the treatment by using this method. Our case have demonstrated, that aggressive conservative treatment approach with combination of: active and adequate drainage of the leak site, systemic antibiotic therapy, nutritional support by feeding gastrostomy with frequent radiologic examinations for monitoring of healing process is the effective and safe treatment of esophageal leaks.
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Ann Med
December 2025
Department of Thoracic Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Background: The purpose of this study was to investigate the safety and efficacy of left thoracic approach (LTA) and right thoracic approach (RTA) in patients with esophageal squamous cell carcinoma (ESCC) after neoadjuvant immunochemotherapy (NICT).
Methods: This study included 83 ESCC patients who underwent right transthoracic esophagectomy ( = 61) and left transthoracic esophagectomy ( = 22) after NICT in our hospital from October 2019 to September 2023. The data of these patients were retrospectively analyzed.
J Clin Med
January 2025
2nd Department of General Surgery and Surgical Oncology, Medical University Hospital, 50-556 Wroclaw, Poland.
The management of esophageal cancer (EC) remains a significant clinical challenge, particularly in optimizing therapeutic strategies for different stages and subgroups. This study assessed the impact of preoperative radiochemotherapy (CRT) on clinical staging and identified subgroups for whom definitive CRT (dCRT) may provide a favorable alternative to surgery. Sixty-one patients with esophageal adenocarcinoma or squamous cell carcinoma were enrolled.
View Article and Find Full Text PDFCancers (Basel)
January 2025
Department of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Esophageal cancer (EC) is one of the leading causes of cancer-related deaths globally. Surgery is the standard treatment for resectable EC after preoperative chemoradiotherapy or chemotherapy, followed by postoperative adjuvant chemotherapy in certain cases. Upper gastrointestinal endoscopy and computed tomography (CT) are predominantly performed to evaluate the efficacy of these treatments, but their sensitivity and accuracy for evaluating minimal residual disease remain unsatisfactory, thereby requiring the development of alternative methods.
View Article and Find Full Text PDFPLoS One
January 2025
Cardiovascular Outcomes Research Laboratories (CORELAB), University of California, Los Angeles, Los Angeles, CA, United States of America.
Purpose: Patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) have been noted to face increased cancer incidence. Yet, the impact of concomitant renal dysfunction on acute outcomes following elective surgery for cancer remains to be elucidated.
Methods: All adult hospitalizations entailing elective resection for lung, esophageal, gastric, pancreatic, hepatic, or colon cancer were identified in the 2016-2020 National Inpatient Sample.
Asian J Endosc Surg
January 2025
Division of Advanced Surgical Oncology, Research and Development Center for New Medical Frontiers, Kitasato University School of Medicine, Sagamihara, Japan.
Background: Laparoscopy-assisted distal gastrectomy (LADG) with Billroth I (B-I) reconstruction is frequently performed for gastric cancer. However, the difference between the circular stapler technique (CS) and delta-shaped anastomosis (DA) remains unclear, especially regarding the postoperative endoscopic physiological findings.
Methods: Three hundred and one patients including 150 CS patients and 151 DA patients during LADG with B-I reconstruction between 2013 and 2019 at Saitama Medical University International Medical Center were chosen as study subjects.
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