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Bone matching versus tumor matching in image-guided carbon ion radiotherapy for locally advanced non-small cell lung cancer.

Radiat Oncol

December 2024

Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, NO. 4365 Kang Xin Road, Shanghai, 201315, China.

Background And Purpose: This study evaluates the dosimetric impact of tumor matching (TM) and bone matching (BM) in carbon ion radiotherapy for locally advanced non-small cell lung cancer.

Materials And Methods: Forty patients diagnosed with locally advanced non-small cell lung cancer were included in this study. TM and BM techniques were employed for recalculation based on re-evaluation computed tomography (CT) images of the patients, resulting in the generation of dose distributions: Plan-T and Plan-B, respectively.

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In this paper, we explore the usage of decision aids, patient information leaflets (PILs), videos, social media and modern technology to empower patients and enable shared decision-making (SDM). It explores the role of enhanced consent processes in urology. A re-evaluation of the conventional consent process is required towards more patient-centred care and SDM, which prioritises patient education and understanding of their medical conditions and treatment pathways.

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Observing Carbon Dots in Putative Boron Nitride Quantum Dots.

Nano Lett

December 2024

Laboratory of Materials Science and Nanotechnology (LMNT), Department of Biomedical Sciences, CR-INSTM, University of Sassari, Viale S. Pietro 43C, Sassari 07100, Italy.

Article Synopsis
  • Boron nitride quantum dots (BNQDs) are popular for their promising optical features and biocompatibility, but recent findings suggest many believed BNQDs are actually misidentified carbon dots (CDs).
  • The study examines the synthesis methods of BNQDs using ethanol and -methyl-2-pyrrolidone, revealing that both BNQDs and CDs produced under these conditions share strikingly similar optical properties and chemical compositions.
  • This discrepancy highlights the need for a re-evaluation of existing research on BNQDs and their relationship to the synthesis techniques used in creating BN-based nanomaterials.
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The role of uric acid in the risk of hypertension developed from prehypertension: a five-year Chinese urban cohort study.

Arch Public Health

October 2024

Chronic Disease and Health Management Research Center, Geriatric Hospital of Nanjing Medical University, 65 Jiangsu Road, Nanjing, 210024, Jiangsu Province, China.

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  • * A study involving 1,516 prehypertensive individuals found that over five years, the cumulative incidence of hypertension was 35.1%, with those having high uric acid (hyperuricemia) showing a higher risk (40.7%) compared to those without (34.0%).
  • * The findings suggest that hyperuricemia is an independent risk factor for developing hypertension from a prehypertensive state, especially notable in males, although the association was not significant in females or older participants (
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The scarcity of organ donors relative to the number of patients with End Stage Kidney Disease (ESKD) has led to prolonged waiting times for kidney transplants, contributing to elevated cardiovascular mortality risk. Transplant professionals are tasked with the complex allocation of limited organs to a vulnerable patient group facing heightened morbidity and mortality risk. The need for continuous re-evaluation of waitlisted patients is evident due to the significant number who perish while awaiting transplantation.

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