The purpose of this article was to characterize practices of buprenorphine/naloxone (B/N) diversion in a region with a high prescribing prevalence. A cross-sectional, open-ended survey was administered to individuals entering opioid addiction treatment programs in two New England states. The authors obtained formative information about the knowledge, attitudes, beliefs, practices, and street economy of B/N diversion. The authors interviewed 51 individuals, 49 of which were aware of B/N medication. Of that number, 100% had diverted B/N to modulate opiate withdrawal symptoms arising from attempted "self-detoxification," insufficient funds to purchase preferred illicit opioids, or inability to find a preferred source of drugs. Thirty of 49 (61%) participants obtained the illicit drug from an individual holding a legitimate prescription for B/N. A high proportion of individuals in the study locations who sought treatment for opioid addiction self-reported the purchase and use of diverted B/N. The diversion of B/N may be minimized by modifying educational, treatment, monitoring, and dispensing practices.
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http://dx.doi.org/10.1080/10550880903014767 | DOI Listing |
bioRxiv
September 2024
Sarah W. Stedman Nutrition and Metabolism Center & Duke Molecular Physiology Institute, Duke University Medical Center.
Acta Neurochir (Wien)
January 2024
Department of Neurosurgery, Oslo University Hospital-Rikshospitalet, P.O. Box 4950, N-0424, Oslo, Norway.
Background: The role of reduced intracranial compliance (ICC) in the outcome after foramen magnum decompression (FMD) was demonstrated in adults with Chiari malformation Type 1 (CMI). However, similar observations from children treated for CMI are missing.
Methods: We reviewed pediatric cases of CMI referred to FMD between 2006 and 2022.
Sci Rep
December 2023
Chongqing Water Resources and Electric Engineering College, Yongchuan, 402160, Chongqing, China.
This paper proposes the design of a helical hedge flow channel with a high energy loss, which shows promising potential for application in fruit tree root emitters. The aim is to investigate the relationship between the energy loss form in the channel and its influencing factors. The hydraulic performance testing method is employed to analyze the factors that affect energy loss.
View Article and Find Full Text PDFDrug Alcohol Depend Rep
June 2022
Cambridge Health Alliance, Harvard Medical School, Department of Psychiatry, 1035 Cambridge Street, Suite 21A - CMC, Cambridge, MA 02141, United States.
Background: Increasing buprenorphine/naloxone (B/N) access for opioid use disorder (OUD) is essential yet ensuring adherence and preventing diversion remains challenging. This study examines the feasibility, usability, and acceptability of , a mobile platform integrating motivational coaching, adherence monitoring, and electronic dispensing during office-based B/N treatment.
Methods: In this multi-site randomized controlled trial, provided coaching and supervised self-administration of B/N by mobile recovery coaches (MRCs) via videoconference.
Ann Surg Open
June 2022
From the Department of Surgery, Attikon Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
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