Background: The literature contains only a small number of reports concerning best supportive care(BSC)in gastric cancer. With the progress of social healthcare systems supporting medical care at home, the quality and performance of BSC at present are different from those in the mid-1990s, when the previous reports were published. We evaluated the quality and performance of BSC in gastric cancer patients in collaboration with visiting nurses.
Patients And Methods: This study comprised 17 gastric cancer patients receiving BSC between March 2005 and April 2009. Baseline characteristics were age, sex, performance status, and main disease site at entry. Except for one patient who died of other than gastric cancer, types of nutritional support whenever needed during the BSC period were divided into two categories; drip infusion through peripheral vein (peripheral group, n=7) and parenteral or enteral nutrition through a central venous catheter or gastrostomy (hyperalimentation group, n=9). The main outcome measures were overall survival and survival according to the type of nutritional support, as well as quality and performance of BSC.
Results: Mean age and mean PS were 76 years old and 2. 9, respectively, with incidences of > or =75 years old and PS> or =3 accounting for 71% and 59%, respectively. Overall MST was 175 days, which was longer than earlier reported. MST of the hyperalimentation group (190 days)was significantly (p<0.04) longer than that of the peripheral group. Fourteen patients (88%) could stay at home during at least part of the BSC period, and among them, 10 patients received home visiting care by a doctor and/or nurse, and 7 patients (70%) died at home. Eight patients (89%) in the hyperalimentation group received home care visits.
Conclusions: These results suggest that home care hyperalimentation by visiting nurses prolongs BSC patient survival in gastric cancer. Domiciliary care realizes hyperalimentation and provides comprehensive home-care during BSC period.
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Int J Health Sci (Qassim)
January 2025
Department of Oncologic Pathology, South Egypt Cancer Institute, Assiut University, Assiut, Egypt.
Objective: Gastrointestinal stromal tumor (GIST) is the most common type of mesenchymal tumor accounting for 2.2% of all malignant gastric tumors. Mesenchymal stem cells (MSCs) play crucial roles in gastric carcinogenesis.
View Article and Find Full Text PDFAnn Gastroenterol Surg
January 2025
Department of Gastroenterological Surgery, Gastroenterological Center, Cancer Institute Hospital Japanese Foundation for Cancer Research Tokyo Japan.
Background: The standard adjuvant chemotherapy regimen for stage III gastric cancer is docetaxel plus S-1 (DS) based on the results of the START-II trials. However, in clinical practice some patients could not continue this intensive doublet chemotherapy because of limited tolerability. This study aimed to assess the practical feasibility of DS and elucidate the predictive factors for the completion of adjuvant DS therapy.
View Article and Find Full Text PDFAnn Gastroenterol Surg
January 2025
Aim: The reconstruction methods after proximal gastrectomy (PG) are varied but not standardized. This study was performed to evaluate the short-term clinical outcomes between double tract reconstruction (DTR) and double flap technique (DFT).
Methods: We retrospectively reviewed and collected data of patients who underwent DTR and DFT after laparoscopic proximal gastrectomy (LPG), respectively, between January 2020 and March 2023.
Ann Gastroenterol Surg
January 2025
The Japan Society for Endoscopic Surgery Tokyo Japan.
Background: The advantages of robot-assisted minimally invasive esophagectomy (RA-MIE) over conventional minimally invasive esophagectomy (C-MIE) are unknown. This nationwide large-scale study aimed to compare surgical outcomes between RA-MIE and C-MIE using rigorous propensity score methods, including detailed covariates and relevant outcomes.
Methods: This Japanese nationwide retrospective cohort study included RA-MIE or C-MIE for esophageal malignant tumors performed between October 2018 and December 2019 and registered in the Japanese National Clinical Database.
Aim: In this study, we evaluated the difference in short-term outcomes and postoperative nutritional status between subtotal gastrectomy (sTG) and proximal gastrectomy (PG) to determine the optimal surgical treatment for early gastric cancer in the upper third of the stomach.
Methods: Patients who underwent laparoscopic or robotic sTG or PG at the Shizuoka Cancer Center in Shizuoka between January 2014 and December 2020 were enrolled in this retrospective study. Patient characteristics, surgical outcomes, endoscopic findings, and postoperative nutritional changes, including blood tests, body weight, psoas muscle, and subcutaneous and visceral adipose tissue, were measured and compared between the two groups.
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