A method for the estimation of the human intake of trihalomethanes (THMs), namely chloroform, bromodichloromethane, dibromochloromethane and bromoform, during showering and bathing is reported. The method is based on the determination of these compounds in exhaled breath that is collected by solid adsorption on Tenax using a device specifically designed for this purpose. Instrumental measurements were performed by automatic thermal desorption coupled to gas chromatography with electron capture detection. THMs in exhaled breath samples were determined during showering and swimming pool attendance. The levels of these compounds in indoor air and water were also determined as reference for interpretation of the exhaled breath results. The THM concentrations in exhaled breath of the volunteers measured before the exposure experiments showed a close correspondence with the THMs levels in indoor air where the sampler was located. Limits of detection in exhaled breath were dependent on THM analytes and experimental sites. They ranged between 170 and 710 ng m(-3) in the swimming pool studies and between 97 and 460 ng m(-3) in the showering studies. Application of this method to THMs determination during showering and swimming pool activities revealed statistically significant increases in THMs concentrations when comparing exhaled breath before and after exposure.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.aca.2009.12.040 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Visual detection of Mycobacterium tuberculosis in exhaled breath using N95 enrichment respirator, RPA, and lateral flow assay.
Talanta
December 2024
The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou 510317, China. Electronic address:
Tuberculosis (TB) is the second deadliest infectious disease worldwide. Current TB diagnostics utilize sputum samples, which are difficult to obtain, and sample processing is time-consuming and difficult. This study developed an integrated diagnostic platform for the rapid visual detection of Mycobacterium tuberculosis (Mtb) in breath samples at the point-of-care (POC), especially in resource-limited settings.
View Article and Find Full Text PDFExhaled Breath Analysis Using a Novel Electronic Nose for Different Respiratory Disease Entities.
Lung
January 2025
Department of Internal Medicine, National Taiwan University Hospital, No.7, Chung Shan S. Rd., Zhongzheng District, Taipei City, 100225, Taiwan.
Purpose: Electronic noses (eNose) and gas chromatography mass spectrometry (GC-MS) are two important breath analysis approaches for differentiating between respiratory diseases. We evaluated the performance of a novel electronic nose for different respiratory diseases, and exhaled breath samples from patients were analyzed by GC-MS.
Materials And Methods: Patients with lung cancer, pneumonia, structural lung diseases, and healthy controls were recruited (May 2019-July 2022).
A handheld biofluorometric system for acetone detection in exhaled breath condensates.
Analyst
January 2025
Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.
As a marker of human metabolism, acetone is important for lipid metabolism monitoring and early detection of diabetes. In this study, we developed a handheld biosensor for acetone based on fluorescence detection by utilizing the enzymatic reaction of secondary alcohol dehydrogenase (S-ADH) with β-nicotinamide adenine dinucleotide (NADH, = 340 nm, = 490 nm). In the reaction, NADH is oxidized when acetone is reduced to 2-propanol by S-ADH, and the acetone concentration can be measured by detecting the amount of NADH consumed in this reaction.
View Article and Find Full Text PDFQuartz-Enhanced Photoacoustic Spectroscopy-Based Acetone and Ammonia Measurements from Human Breath Near 8 μm Wavelength Band.
ACS Sens
January 2025
Department of Engineering Design, Indian Institute of Technology Madras, Chennai 600036, India.
Human breath gas analysis is a noninvasive disease diagnostic approach used to identify different pathological conditions in the human body. Monitoring breath acetone (CHO) and ammonia (NH) as biomarkers is vital in diagnosing diabetes mellitus and liver disorders, respectively. In this article, the quartz-enhanced photoacoustic spectroscopy (QEPAS) technique is proposed and demonstrated for measuring CHO and NH in human exhaled breath samples.
View Article and Find Full Text PDFA Doped Surface Ionization Method for Ion Mobility Spectrometry.
Rapid Commun Mass Spectrom
March 2025
State Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, China.
Rationale: Exhaled breath can be used for early warning of disease, with organic nitrogen compounds, including triethylamine (TEA), being linked to various medical conditions. Surface ionization ion mobility spectrometry (SI-IMS) facilitates the direct detection of TEA in exhaled breath. However, the presence of multiple ionization products of TEA poses challenges for both quantitative and qualitative analyses.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!