Triplex-stabilizing properties of parallel clamps carrying LNA derivatives at the Hoogsteen strand.

Chem Biodivers

Institute for Research in Biomedicine, IQAC-CSIC, CIBER-BBN Networking Centre on Bioengineering, Biomaterials and Nanomedicine, Edifici Helix, Baldiri Reixac 15, ES-08028 Barcelona, Spain.

Published: February 2010

DNA Parallel clamps with a polypurine strand linked to a polypyrimidine Hoogsteen strand containing locked nucleic acids bind their corresponding polypyrimidine targets with high affinity.

Download full-text PDF

Source
http://dx.doi.org/10.1002/cbdv.200900230DOI Listing

Publication Analysis

Top Keywords

parallel clamps
8
hoogsteen strand
8
triplex-stabilizing properties
4
properties parallel
4
clamps carrying
4
carrying lna
4
lna derivatives
4
derivatives hoogsteen
4
strand dna
4
dna parallel
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!