In vitro TAXOL production, by Pestalotiopsis breviseta--a first report.

Fitoterapia

Department of Biotechnology, Vels University, Pallavaram, Chennai 6OO 117, Tamilnadu, India.

Published: September 2010

Coelomycetous fungi were screened for the production of TAXOL. TAXOL production of Pestalotiopsis breviseta fungi is confirmed by Ultra Violet (UV) spectroscopic analysis, Infra Red (IR) analysis, high performance liquid chromatography (HPLC), nuclear magnetic resonance (NMR) and LC-MASS spectroscopy. TAXOL isolated from the P. breviseta fungus was identical with authentic TAXOL and produces 0.064 mg/L (0.128% dry weight of fungal mat).

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Source
http://dx.doi.org/10.1016/j.fitote.2010.01.021DOI Listing

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