Background: The study of geographic variations in the use of medication can constitute an interesting and useful option in public health surveillance for the identification of population needs and for the fair partition of resources. Many studies report variations in the use of medication that are not always understood. Considering the importance of medication, particularly for chronic diseases like asthma, it is important to identify factors that can explain geographic differences in the utilization of medications in order to determine optimal prescription practices.
Methods: We used a multilevel analysis to explore determinants of variation among welfare recipients and subscribers covered by the Quebec public drug plan, aged five to 44, who claimed at least one prescription for an asthmatic medication in 2003. The analysis was based on 73 small areas in Quebec's 15 health regions.
Results: Prevalence of usage and hospitalization rates are the main predictors of variation in medication intensity. On the other hand, prevalence of usage is related to the area of residence, proportion of welfare recipients and prevalence of smokers. The quality of medication is related to practitioners' specialty.
Conclusion: Different factors contribute to the understanding of geographic variations in asthma medication but it remains important to control for severity. Small area analysis makes it possible to identify specific areas facing more important problems in the prevalence and use of medication for asthma and thus leads to better understanding of local needs for more targeted interventions.
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http://dx.doi.org/10.1016/j.rmr.2009.11.005 | DOI Listing |
Curr Issues Mol Biol
December 2024
College of Forestry, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
is an endangered tree species, and detecting its genetic diversity can reveal the mechanisms of endangerment, providing references for the conservation of genetic resources. Samples of 137 trees across seven populations within Fujian Province were collected and sequenced using double-digest restriction site-associated DNA (ddRAD-seq). A total of 3,687,189 single-nucleotide polymorphisms (SNPs) were identified, and 15,158 high-quality SNPs were obtained after filtering.
View Article and Find Full Text PDFSleep Med X
December 2025
Research Group 'Chronobiology, Nutrition and Health' of Federal University of Alagoas, Maceió, Alagoas, Brazil.
Objective: To examine the influence of latitude, longitude, sunrise, and daylight, in conjunction with individual and behavioral factors, on sleep duration, wake time, and bedtime in a country with the world's broadest latitude range, yet characterized by homogeneity in language, cultural traits, and consistent time zones.
Methods: Participants (n = 1440; 18-65y) were part of a virtual population-based survey (2021-22). Sleep patterns were spatially represented through maps using Multilevel B-spline Interpolation.
Front Pediatr
January 2025
Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Introduction: Infantile Epileptic Spasms Syndrome (IESS) typically has a profound impact on the neurodevelopment of patients. The study on IESS indicates possible geographical variation in etiology and a lack of data from China. Our study intends to summarize the etiology of IESS and analyze its characteristics.
View Article and Find Full Text PDFPublic Health Pract (Oxf)
June 2025
Wolfson Institute of Population Health, Queen Mary University of London, London, UK.
Objectives: Private healthcare is a rapidly growing industry in the UK, particularly for surgical procedures, due to extensive waiting times in publicly funded health care. The NHS also commissions private healthcare to provide procedures for NHS patients to alleviate waiting times. We aimed to explore the trends and geographical variations between the North and South of England in privately funded and NHS-funded privately delivered orthopaedic procedures compared to NHS waiting times.
View Article and Find Full Text PDFEuro Surveill
January 2025
Medicines and Healthcare products Regulatory Agency (MHRA), South Mimms (Potters Bar), United Kingdom.
In 2024, circulating vaccine-derived poliovirus type 2 (cVDPV2) was detected in wastewater samples in Finland, Germany, Poland, Spain and the United Kingdom (UK). All strains were genetically linked, but sequence analysis showed high genetic diversity among the strains identified within individual wastewater sites and countries and an unexpected high genetic proximity among isolates from different countries. Taken together these results, with sequential samples having tested positive in various sites, a broader geographic distribution beyond positive sampling sites must be considered.
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