AI Article Synopsis
- The study focused on identifying acute self-limited hepatitis B (ASL-HB) in patients with hepatitis B virus-related acute hepatitis, analyzing data from 220 patients.
- Among the 164 diagnosed with acute hepatitis B (AHB), 160 were confirmed as ASL-HB, with a very low percentage progressing to chronic hepatitis B or complications.
- The study noted that AHB cases outnumbered acute infections from hepatitis A and E, with similar symptoms across all types but distinct differences in biochemical parameters; additionally, AHB infections did not show a seasonal peak like HA and HE.
Article Abstract
This study aimed to identify acute self-limited hepatitis B (ASL-HB) among patients presenting with hepatitis B virus (HBV)-related acute hepatitis. Data were available for 220 patients diagnosed with HBV-related acute hepatitis, of whom 164 had acute hepatitis B (AHB). Of these, 160 were confirmed as ASL-HB: three (1.9%) evolved to chronic hepatitis B and one (0.6%) developed fulminant hepatitis and died. Comparisons were also made between AHB and acute infections with hepatitis A (HA) and hepatitis E (HE) viruses. During the study period, the number of patients with AHB exceeded the sum of those with acute HA and acute HE infections. There was no distinct seasonal peak for AHB infection, whereas both acute HA and acute HE infections occurred more frequently in the spring. Clinical symptoms and physical signs were similar for all three types of hepatitis, but significant differences were seen in some biochemical parameters. In conclusion, this study suggests that symptomatic AHB is not rare in China but it seldom evolves to chronic hepatitis B.
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| http://dx.doi.org/10.1177/147323000903700633 | DOI Listing |
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