Blood flow in heart and main vessels is a self-organizing eddy flow described by Kiknadze-Krasnov's non-stationary hydrodynamic equations. Their exact solutions are applicable to simulation of blood circulation in normal and pathological conditions, quantitative evaluation of efficiency of surgical treatment of cardiovascular diseases, and designing implantable devices for cardiovascular surgery to support physiological blood flow structure. An essentially new all-flow three-leaflet CorBit artificial heart valve from pyrolyitic carbon has been proposed to maintain physiological blood flow with minimal regurgitation and transvalvular pressure gradient. The CorBit valve allows to normalize hemodynamic parameters soon after implantation. Also, manufacture is underway of a wide range of original stented and stentless bioprostheses of heart valves and valve-containing BioLab conduits from allogenic and xenogenic biological tissues. BioLab bioprostheses are currently widely used to treat complicated congenital and acquired forms of cardiopathology.

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